encyclopedia of medical concepts
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Cyclobutanes

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Definition:   includes cyclobutenes   
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
1,3-bis(4-isobutyramidobenzamido)-2,4-bis(3-methoxy-4-(thiophene-2-carbonyloxy)phenyl)cyclobutane-1,3-dicarboxylic acid  0   *Cyclobutanes *Phthalic Acids. J Med Chem. 2012 Jan 12;55(1):250-67.
3,4-bis(isoproylamino)cyclobut-3-ene-1,2-dione  0   *Cyclobutanes *Propylamines. Spectrochim Acta A Mol Biomol Spectrosc. 2011 Dec;83(1):472-7
N-(3-(5-cyano-6-methylpyridin-2-yloxy)-2,2,4,4-tetramethylcyclobutyl)imidazo(1,2-a)pyrimidine-3-carboxamide  0   *Cyclobutanes *Bicyclo Compounds, Heterocyclic Androgen Receptor Antagonists. J Med Chem. 2011 Nov 10;54(21):7705-12.
N-(3-((5-cyano-6-methylpyridin-2-yl)oxy)-2,2,4,4-tetramethylcyclobutyl)imidazo(1,2-a)pyrimidine-3-carboxamide  0   *Cyclobutanes *Bicyclo Compounds, Heterocyclic Androgen Receptor Antagonists. J Med Chem. 2011 Nov 10;54(21):7693-704.
N,N-(3-(3-chloro-4-cyanophenoxy)-2,2,4,4-tetramethylcyclobutyl)-1-(2-(methylamino)-2-oxoethyl)-1H-pyrazole-3-carboxamide  0   *Cyclobutanes *Pyrazoles Androgen Receptor Antagonists. J Med Chem. 2011 Nov 10;54(21):7693-704.
3-fluoro-3-(3-fluoro-4-(pyrrolidin-1-ylmethyl)phenyl)-N-(2-methylpropyl)cyclobutanecarboxamide  0   *Cyclobutanes *Pyrrolidines Histamine H3 Antagonists. J Med Chem. 2011 Nov 10;54(21):7602-20.
N-ethyl-3-fluoro-3-(3-fluoro-4-(pyrrolidinylmethyl)phenyl)cyclobutanecarboxamide  0   *Cyclobutanes *Pyrrolidines Histamine H3 Antagonists. J Med Chem. 2011 Nov 10;54(21):7602-20.
NMK 36  0   *Amino Acids *Cyclobutanes. Ann Nucl Med 2011 Jul;25(6):414-8
1-(hydroxymethyl)-3-(3-octylphenyl)cyclobutane  0   *Benzene Derivatives *Cyclobutanes Receptors, Lysosphingolipid/antagonists & inhibitors. J Pharmacol Exp Ther 2011 Sep;338(3):879-89
MEO322 compound  0   *Cyclobutanes *Sialic Acids. Angew Chem Int Ed Engl 2011 Jul 11;50(29):6519-21
SEP 225289  0   *Amines *Cyclobutanes. Int J Neuropsychopharmacol 2011 Mar;14(2):211-23
1,3-diborata-2,4-diphosphoniocyclobutane  0   *Borates *Cyclobutanes. J Phys Chem A. 2011 May 5;115(17):4511-20
di-N-methyl-N-hydroxyethylaniline squaraine  0   *Aniline Compounds *Cyclobutanes *Phenols. Analyst. 2011 May 7;136(9):1916-21
MRT67307  0   *Cyclobutanes *Morpholines. Am J Physiol Gastrointest Liver Physiol. 2011 Feb;300(2):G253-63
1,2-bis(trimethylsilyloxy)cyclobutene  0   *Cyclobutanes *Trimethylsilyl Compounds. Org Lett. 2011 Feb 4;13(3):526-9
1,2-dianilinosquairane  0   *Aniline Compounds *Cyclobutanes. J Phys Chem A. 2010 Sep 23;114(37):10097-109
3,4-diaminocyclobut-3-ene-1,2-dione  0   *Cyclobutanes. Curr Top Med Chem. 2010;10(13):1339-50
cyclobutenone  0   *Cyclobutanes. J Am Chem Soc 2010 Aug 18;132(32):11004-5
2-dodecylcyclobutanol  0   *Cyclobutanes. J Food Sci 2010 May;75(4):T72-80
dictazole B  0   *Cyclobutanes *Indole Alkaloids. J Org Chem. 2010 Apr 2;75(7):2399-402
dictazole A  0   *Cyclobutanes *Indole Alkaloids. J Org Chem. 2010 Apr 2;75(7):2399-402
5-(4-aminophenyl)-4-(3-methyl-3-phenylcyclobutyl)thiazol-2-amine  0   *Cyclobutanes *Thiazoles. J Mol Model 2009 Dec;15(12):1435-45
1-((4-((((3-Isopropyl-2-oxo-2,3-dihydro-1H-benzimidazol-1-yl)carbonyl)amino)methyl)piperidin-1-yl)methyl)cyclobutanecarboxylic acid  0   *Benzimidazoles *Cyclobutanes *Piperidines. Pharmacol Res. 2009 Oct;60(4):237-46
SCH 479833  0   *Benzamides *Cyclobutanes Receptors, Interleukin-8A/antagonists & inhibitors Receptors, Interleukin-8B/antagonists & inhibitors. Clin Cancer Res 2009 Apr 1;15(7):2380-6
(1S,2S)-1-amino-2-hydroxycyclobutanecarboxylic acid  0   *Amino Acids *Cyclobutanes. Org Biomol Chem. 2009 Jul 21;7(14):2885-93
2-aminocyclobutanecarboxylic acid  0   *Carboxylic Acids *Cyclobutanes. J Org Chem. 2009 Apr 17;74(8):3152-5
1-ethoxycarbonyl-4-phenylcyclobutene  0   *Cyclobutanes. J Am Chem Soc. 2009 May 20;131(19):6664-5
4-methyl-1,3,3-triethoxycarbonylcyclobutene  0   *Cyclobutanes. J Am Chem Soc. 2009 May 20;131(19):6664-5
4-phenyl-1,3,3-triethoxycarbonylcyclobutene  0   *Cyclobutanes. J Am Chem Soc. 2009 May 20;131(19):6664-5
endiandrin B  0   *Cyclobutanes *Lignans. Bioorg Med Chem 2009 Feb 1;17(3):1387-92
cyclobutanol  0   *Cyclobutanes. Spectrochim Acta A Mol Biomol Spectrosc 2008 Dec 15;71(4):1379-89
Boc5 compound  0   *Cyclobutanes. PLoS ONE 2008;3(8) (dup#6):e2892
bis(3,5-diiodo-2,4,6-trihydroxyphenyl)squaraine  0   *Phenols *Cyclobutanes. J Photochem Photobiol B 2008 Sep 18;92(3):153-9
1-amino-3-iodomethylene-cyclobutane-1-carboxylic acid  0   *Carboxylic Acids *Cyclobutanes. Bioorg Med Chem Lett 2008 Feb 15;18(4):1264-8
1-amino-3-(2-iodoethenyl)cyclobutane-1-carboxylic acid  0   *Carboxylic Acids *Cyclobutanes. Bioorg Med Chem Lett 2008 Feb 15;18(4):1264-8
KSQ-3  0   *Cyclobutanes *Heterocyclic Compounds, 3-Ring. Anal Sci. 2008 Feb;24(2):213-7
KSQ-4  0   *Cyclobutanes *Heterocyclic Compounds, 3-Ring. Anal Sci. 2008 Feb;24(2):213-7
squaric acid amide  0   *Cyclobutanes *Sulfonamides. Bioorg Med Chem Lett. 2007 Nov 15;17(22):6151-4
perfluorocyclobutane  0   *Cyclobutanes *Fluorocarbons. J Phys Chem A. 2007 Nov 8;111(44):11328-41
3-(1-heptylcyclobutyl)-6a,7,10,10a-tetrahydro-6,6,9-trimethyl-6H-dibenzo(b,d)pyran-1-ol  0   *Benzopyrans *Cyclobutanes. J Med Chem 2007 Aug 23;50(17):4048-60
3-(1-hexylcyclobutyl)-6a,7,10,10a-tetrahydro-6,6,9-trimethyl-6H-dibenzo(b,d)pyran-1-ol  0   *Benzopyrans *Cyclobutanes. J Med Chem 2007 Aug 23;50(17):4048-60
3-amino-4-(2-(2-(4-benzylpiperazin-1-yl)-2-oxoethoxy)phenylamino)cyclobutenedione  0   *Benzyl Compounds *Cyclobutanes. Bioorg Med Chem Lett 2007 Jun 15;17(12):3367-72
endiandrin A  0   *Cyclobutanes *Lignans. J Nat Prod 2007 Jul;70(7):1118-21
1,3-disilacyclobutane  0   *Cyclobutanes *Organosilicon Compounds. J Phys Chem A Dyn Kinet Environ Chem Spectrosc Struct Theory 2007 Feb 8;111(5):825-31
N-(3-(3-methoxyphenyl)-3-phenyl-2-propenyl)cyclobutanecarboxamide  0   *Benzylidene Compounds *Cyclobutanes Receptor, Melatonin, MT2/antagonists & inhibitors. J Med Chem 2006 Dec 14;49(25):7393-403
2-hydroxy-N,N-dimethyl-3-(2-((1-(5-methylfuran-2-yl)propyl)amino)-3,4-dioxocyclobut-1-enylamino)benzamide  0   *Benzamides *Cyclobutanes Receptors, Interleukin-8A/antagonists & inhibitors Receptors, Interleukin-8B/antagonists & inhibitors. J Med Chem 2006 Dec 28;49(26):7603-6
6-(2-hydroxy-3,4-dioxo-1-cyclobutenyl)-3,6,10-triazadodecane-3,10-tetraacetic acid  0   *Cyclobutanes Glycine/*analogs & derivatives. Dalton Trans 2006 Nov 21;(43):5149-55
2-(2-carboxycyclobutyl)glycine  0   *Cyclobutanes Glycine/*analogs & derivatives. J Med Chem 2006 Nov 2;49(22):6532-8
lithium benzocyclobuteneoxide  0   *Cyclobutanes *Organometallic Compounds Lithium. Angew Chem Int Ed Engl. 2005 Sep 12;44(36):5875-8
UK-374503  0   *Benzimidazoles *Cyclobutanes. ChemMedChem. 2006 Jul;1(7):706-9
(cyclobutadiene)tricarbonyliron  0   *Cyclobutanes *Ferric Compounds. Angew Chem Int Ed Engl. 2005 Aug 5;44(31):4929-32
Red-3 compound  0   *Cyclobutanes *Indoles. Electrophoresis 2006 Apr;27(7):1347-54
Red-1c compound  0   *Indoles *Cyclobutanes. Electrophoresis 2006 Apr;27(7):1347-54
4,4'-dihydroxy-alpha-truxillic acid  0   *Cyclobutanes. Biol Pharm Bull 2006 Mar;29(3):489-93
1,1-cyclobutane dicarboxylate  0   *Cyclobutanes *Dicarboxylic Acids. Dalton Trans 2005 Dec 21;(24):3881-5
diethylsilacyclobutane  0   *Cyclobutanes. Langmuir. 2004 Nov 23;20(24):10604-11
L-alpha-(1-cyclobutenyl)glycine  0   *Cyclobutanes Glycine/*analogs & derivatives. Org Lett. 2004 Oct 14;6(21):3659-62
phenylcyclobutadiene  0   *Cyclobutanes. J Am Chem Soc. 2005 Sep 21;127(37):13065-9
tetraazacyclobutadiene  0   *Aza Compounds *Cyclobutanes. Angew Chem Int Ed Engl. 2004 Oct 18;43(41):5485-8
cis-2-(tetradec-5'-enyl)-cyclobutanone  0   *Alkenes *Cyclobutanes. J Agric Food Chem. 2005 Jul 27;53(15):5836-41
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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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