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Acenaphthenes

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Definition: Tricyclic ethylene-bridged naphthalene derivatives. They are found in petroleum residues and coal tar and used as dye intermediates, in the manufacture of plastics, and in insecticides and fungicides.     
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
3-(dimethylamino-ethylamino)-8-oxo-8H-acenaphthol(1,2-b)pyrrole-9-carboxylic acid  0   *Acenaphthenes *Pyrroles Antineoplastic Agents Uterine Cervical Neoplasms/drug therapy. Anticancer Drugs. 2011 Oct;22(9):875-85
5,10,15,20-tetrakis(N-methyl-4-pyridyl)-tetraacenaphthoporphyrin  0   *Acenaphthenes *Porphyrins. Chem Asian J 2011 May 2;6(5):1147-50
ethyl 8-oxo-8H-acenaphtho(1,2-b)pyrrole-9-carboxylate  0   *Acenaphthenes *Pyrroles Receptor, Fibroblast Growth Factor, Type 1/antagonists & inhibitors. J Med Chem 2011 Jun 9;54(11):3732-45
8-oxo-3-thiomorpholin-4-yl-8H-acenaphtho(1,2-b)pyrrole-9-carbonitrile  0   *Acenaphthenes *Pyrroles. Chembiochem 2007 Jan 2;8(1):113-21
3-(3-dimethylaminopropylamino)-8-oxo-8H-acenaphtho(1,2-b)pyrrole-9-carbonitrile  0   *Acenaphthenes *Pyrrolidinones. Chem Res Toxicol 2009 Mar 16;22(3):483-91
3-(4-methylpiperazin)-8-oxo-8H-acenaphtho(1,2-b)pyrrole-9-carbonitrile  0   *Acenaphthenes *Pyrrolidinones. Chem Res Toxicol 2009 Mar 16;22(3):483-91
3-piperidine-8-oxo-8H-acenaphtho-(1,2-b)pyrrole-9-carboxylic acid  0   *Acenaphthenes *Pyrroles. Bioorg Med Chem. 2009 Nov 1;17(21):7615-21
3-(dimethylamino-propylamino)-8-oxo-8H-acenaphtho-(1,2-b)pyrrole-9-carboxylic acid  0   *Acenaphthenes *Pyrroles. Bioorg Med Chem. 2009 Nov 1;17(21):7615-21
bis(1-naphthylimino)acenaphthene  0   *Acenaphthenes. Inorg Chem. 2008 Sep 1;47(17):7734-44
NBI-34041  0   *Acenaphthenes. Neuropsychopharmacology 2007 Sep;32(9):1941-9
bis(N-(4-tolyl)imino)acenaphthene  0   *Acenaphthenes. Spectrochim Acta A Mol Biomol Spectrosc 2007 May;67(1):263-72
5-methoxy-1,2-dihydroacenaphthylen-1-one  0   *Acenaphthenes. Chem Res Toxicol. 2006 Feb;19(2):217-22
5-methoxyacenaphthylene 1,2-oxide  0   *Acenaphthenes *Oxides. Chem Res Toxicol. 2006 Feb;19(2):217-22
bis(N-(2,6-diisopropylphenyl)imino)acenaphthene  0   *Acenaphthenes. Eur J Med Chem. 2005 Dec;40(12):1214-21
2-(3-(1-(acenaphthen-1-yl)piperidin-4-yl)-2,3-dihydro-2-oxobenzimidazol-1-yl)-N-methylacetamide  0   *Acenaphthenes *Benzimidazoles. Br J Pharmacol 2005 Sep;146(1):33-40
6-cyclopropylmethyl-2-(2,4-dichlorophenyl)-7-ethyl-4-methyl-7,8-dihydro-6H-1,3,6,8a-tetraazaacenaphthylene  0   *Acenaphthenes Corticotropin-Releasing Hormone/antagonists & inhibitors. J Med Chem 2005 Sep 8;48(18):5780-93
2-(2,4-dichlorophenyl)-4-methyl-6-(1-propylbutyl)-2,6,7,8-tetrahydro-1,2,3,6-tetraazaacenaphthylene  0   *Acenaphthenes Receptors, Corticotropin-Releasing Hormone/antagonists & inhibitors. J Med Chem 2005 Jun 16;48(12):4100-10
1-(2-chloro-4-methylphenyl)-7-methyl-5-(1-propylbutyl)-1,3,4,5-tetrahydro-1,5,8-triazaacenaphthylene  0   *Acenaphthenes Receptors, Corticotropin-Releasing Hormone/antagonists & inhibitors. J Med Chem 2005 Jun 16;48(12):4100-10
3-(pyridine-2-yl)-as-triazino(5,6-f)acenaphthylene  0   *Acenaphthenes *Triazines. J Inorg Biochem. 2004 Jun;98(6):1143-50
acenaphtheno(1,2-b)-1,4,8,9-tetraazatriphenylene  0   *Acenaphthenes *Phenanthrolines Ligands. J Inorg Biochem 2000 Mar;78(4):293-8
acenaphthenequinone thiosemicarbazone  0   *Acenaphthenes *Thiosemicarbazones. J Inorg Biochem 1997 Apr;66(1):7-17
1-amino-6,7,8,8a-tetrahydroacenaphthene  0   *Acenaphthenes. Boll Chim Farm 1995 Jun;134(6):329-32
6,7,8,8a-tetrahydro-1-aminoacenaphthylene  0   *Acenaphthenes. J Pharm Pharmacol 1994 May;46(5):397-9
8-amino-6(N)-methyl-2-ribofuranosyl-1,2,3,5,6,7-hexaazaacenaphthylene  109947-70-8   *Acenaphthenes *Ribonucleosides. Nucleic Acids Symp Ser 1986;(17):41
acenaphthylene  208-96-8   *Acenaphthenes. Appl Environ Microbiol 1984;48(1):10
acenaphthene  83-32-9   *Acenaphthenes. Appl Environ Microbiol 1984;48(1):10
5-nitroacenaphthene  602-87-9   *Acenaphthenes. Cancer Res 1982;42(4):1243
acenaphtho(1,2-b)quinoxaline-7,12-dioxide  26801-94-5   *Acenaphthenes. Arizona Med 29(5):406;1972
acenaphthene-1-ol  6306-07-6   *Acenaphthenes. Xenobiotica 3(10):633;1973
acenaphthenequinone  82-86-0   *Acenaphthenes.
(1,2)-acenaphthenediol  17976-92-0   *Acenaphthenes. Biochem J 121(1):4P;1971
triciribine phosphate  61966-08-3 1,4,5,6,8-Pentaazaacenaphthylen-3-amine, 1,5-dihydro-5-methyl-1-(5-O-phosphono-beta-D-ribofuranosyl)  *Acenaphthenes *Ribonucleotides. J Biol Chem 252(6):2010;1977

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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