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ψ
ψ
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Hydroxybutyrates
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Definition
: Salts and esters of hydroxybutyric acid.
Examples
Sodium Oxybate
Substance
CAS Registry & name
Categories
Source
Drugs
*
N-
(2-
(4-
((3-
chloro-
4-
(3-
(trifluoromethyl)phenoxy)phenyl)amino)-
5H-
pyrrolo(3,2-
d)pyrimidin-
5-
yl)ethyl)-
3-
hydroxy-
3-
methylbutanamide
0
*Hydroxybutyrates
*Bicyclo Compounds, Heterocyclic
Receptor, Epidermal Growth Factor/antagonists & inhibitors.
J Med Chem. 2011 Dec 8;54(23):8030-50.
4-
(1-
(4-
fluorobenzyl)-
4-
hydroxy-
1H-
indol-
3-
yl)-
2-
hydroxy-
4-
oxobut-
2-
enoic acid
0
*Hydroxybutyrates
*Indoles.
Antiviral Res. 2011 Oct;92(1):102-7.
6-
tuliposide B
0
*Glucosides
*Hydroxybutyrates.
Phytochemistry 2010 Feb;71(2-3):312-24
hydroxy wilfordic acid
0
*Hydroxybutyrates
Niacin/*analogs & derivatives.
Arch Pharm Res 2009 Dec;32(12):1673-9
2-
(1-
(3-
(4-
(biphenyl-
4-
carbonyl)-
2-
propylphenoxy)propyl)-
1,2,3,4-
tetrahydroquinolin-
5-
yloxy)-
2-
methylpropionic acid
0
*Hydroxybutyrates
*Quinolines
PPAR gamma/agonists.
J Med Chem 2009 Apr 23;52(8):2618-22
3-
hydroxybutyrate methyl ester
0
*Hydroxybutyrates.
Biomaterials. 2009 Mar;30(8):1532-41
3-
Hydroxyisobutyric aciduria
0
*Amino Acid Metabolism, Inborn Errors
Hydroxybutyrates/urine.
ethyl 4,4,4-
trifluoro-
3-
hydroxybutanoate
0
*Hydroxybutyrates.
Biotechnol J 2007 Feb;2(2):260-5
4-
pyridyl-
2-
oxo-
4-
hydroxyisovaleric acid
0
*Hydroxybutyrates
*Pyridines.
Biochem Biophys Res Commun 2007 Sep 14;361(1):196-201
ethyl (2S,3S)-
3-
hydroxy-
2-
methylbutanoate
0
*Hydroxybutyrates.
Acta Biol Hung. 2007 Jun;58(2):219-23
methyl alpha-
hydroxyisobutyrate
0
*Hydroxybutyrates.
Phys Chem Chem Phys 2006 Oct 14;8(38):4449-60
4-
chloro-
3-
hydroxybutyric acid
0
*Hydroxybutyrates.
J Biosci Bioeng 2006 Feb;101(2):97-103
3,6-
(3-
hydroxy-
5-
oxa-
1,4-
dioxo-
6-
phenyl-
2-
hexenyl)-
4(1H)-
quinolinone
0
*Hydroxybutyrates
*Quinolones.
J Med Chem 2006 Mar 23;49(6):1939-45
4-
(1,3-
dibenzyl-
1,2,3,4-
tetrahydro-
2,4-
dioxopyrimidin-
5-
yl)-
2-
hydroxy-
4-
oxobut-
2-
enoic acid
0
*Hydroxybutyrates
Uracil/*analogs & derivatives.
J Med Chem 2006 Jan 26;49(2):445-7
2,3,4-
trihydroxybutanamide
0
*Hydroxybutyrates.
FEMS Immunol Med Microbiol 2005 Jul 1;45(1):71-4
(S)-
(-
)-
4-
(2-
benzimidazolyl)-
4-
hydroxybutyric acid
0
*Benzimidazoles
*Hydroxybutyrates.
Basic Clin Pharmacol Toxicol. 2005 Apr;96(4):325-30
ethyl 3-
hydroxy-
2-
oxobutanoate
0
*Hydroxybutyrates.
Pest Manag Sci 2005 Apr;61(4):407-12
ethyl 3-
methyl-
3-
hydroxy-
2-
oxobutanoate
0
*Hydroxybutyrates.
Pest Manag Sci 2005 Apr;61(4):407-12
methyl-
4-
bromo-
3-
hydroxybutyrate
0
*Hydroxybutyrates.
Appl Microbiol Biotechnol 2004 Nov;66(1):53-62
gamma-
(4-
methoxybenzyl)-
gamma-
hydroxybutyric acid
0
*Hydroxybutyrates.
J Neurochem 2003 Nov;87(3):722-32
2-
amino-
4-
(3'-
hydroxyphenyl)-
4-
hydroxybutanoic acid
0
*Hydroxybutyrates
*Phenylbutyrates.
Bioorg Med Chem Lett 2002 Feb 11;12(3):361-3
ethyl 3-
hydroxybutyrate
0
*Hydroxybutyrates
Stereoisomerism.
Biotechnol Bioeng 2001 Aug 5;74(3):256-63
poly(3-
hydroxybutyrate-
co-
3-
hydroxypropionate)
0
*Hydroxybutyrates
*Polyesters.
Int J Biol Macromol 2001 Mar 14;28(3):235-43
4-
hydroxy-
4-
(3-
pyridyl)butanoic acid
0
*Hydroxybutyrates
*Pyridines.
Chem Res Toxicol 1999 Feb;12(2):164-71
2,4-
di-
O-
acetyl-
3-
deoxy-
glycero-
tetronic acid
0
*Hydroxybutyrates.
Carbohydr Res 1998 Jan;306(1-2):163-70
4-
hydroxybutyric acid
591-81-1
*Hydroxybutyrates.
phenytoin-
bis-
hydroxyisobutyrate
0
*Hydroxybutyrates
Phenytoin/*analogs & derivatives.
Pharm Res 1997 Feb;14(2):251-3
T 8581
0
*Hydroxybutyrates
*Triazoles.
Antimicrob Agents Chemother 1997 Jan;41(1):30-4
2-
ethyl-
2-
hydroxybutyric acid
3639-21-2
*Hydroxybutyrates.
Carcinogenesis 1994 Sep;15(9):1773-8
poly(3-
hydroxybutanoate)
0
*Hydroxybutyrates
*Polyesters.
Eur J Biochem 1994 Sep 1;224(2):317-28
harzianic acid
157148-06-6
Hydroxybutyrates
Pyrroles.
J Antibiot (Tokyo) 1994 Jun;47(6):731-2
2,2-
dimethyl-
3-
hydroxybutyric acid
29269-83-8
*Hydroxybutyrates.
Eur J Drug Metab Pharmacokinet 1991 Jul-Sep;16(3):189-96
3-
carboxy-
5-
methyl-
N-
(4-
(trifluoromethyl)phenyl)-
4-
isoxazolecarboxamide
134888-93-0
*Aniline Compounds
*Hydroxybutyrates.
J Med Chem 1992 Feb 7;35(3):507-10
A 771726
108605-62-5
*Aniline Compounds
*Hydroxybutyrates.
Pharma Action
Anti-Inflammatory Agents, Non-Steroidal
;
Immunosuppressive Agents
J Med Chem 1992 Feb 7;35(3):507-10
poly(3-
hydroxybutyrate-
co-
4-
hydroxybutyrate)
117068-64-1
*Hydroxybutyrates
*Polyesters.
Int J Biol Macromol 1990;12(2):106
technetium Tc 99m 2-
hydroxyisobutyric acid
0
*Hydroxybutyrates
*Organotechnetium Compounds.
Int J Rad Appl Instrum (A) 1990;41(2):221
technetium Tc 99m 2-
ethyl-
2-
hydroxybutyric acid
0
*Hydroxybutyrates
*Organotechnetium Compounds.
Int J Rad Appl Instrum (A) 1990;41(2):221
thrazarine
120128-14-5
Hydroxybutyrates
Serine/analogs & derivatives.
J Antibiot (Tokyo) 1988;41(11):1568
acetyl acetonate
17272-66-1 2,4-
Pentanedione, ion(1-
)
*Hydroxybutyrates
*Pentanones
Allergens.
Contact Dermatitis 1986;14(4):263
3,4-
dihydroxybutanoic acid
1518-61-2
*Hydroxybutyrates.
Am J Physiol 1984;246(4 pt 2):R542
3-
hydroxy-
3-
cyclohexylbutyric acid
17692-20-5
*Hydroxybutyrates.
J Med Chem 1983;26(12):1764
4-
arsono-
2-
hydroxybutanoic acid
86880-38-8 Butanoic acid, 4-
arsono-