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Uracil

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Definition:   /biosyn /physiol permitted; uracil deoxyriboside, uracil deoxyribonucleoside   
Examples Bromouracil; Fluorouracil; Hydroxyphenylazouracil; Orotic Acid; Pentoxyl; Thiouracil; Thymine; Uracil Mustard
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
5-(pyren-1-yl)uracil  0   *Pyrenes Uracil/*analogs & derivatives. Chem Asian J. 2011 Dec 2;6(12):3251-9
CE 224,535  0   *Benzamides Uracil/*analogs & derivatives Purinergic P2X Receptor Agonists. Bioorg Med Chem Lett 2011 Jun 15;21(12):3708-11
1-benzoylmethyl-5-(N-pyrrolidino)uracyl  0   *Pyridines Uracil/*analogs & derivatives. Eksp Klin Farmakol. 2011;74(2):16-8
5-fluoro-6-((2-iminopyrrolidin-1-yl)methyl)uracil  0   *Pyrrolidines Uracil/*analogs & derivatives Fluorine Radioisotopes Thymidine Phosphorylase/antagonists & inhibitors. Nucleosides Nucleotides Nucleic Acids 2010 Jan;29(1):49-54
5-(2-pyridylethynyl)uracil  0   *Pyridines Uracil/*analogs & derivatives. J Med Chem 2010 Aug 26;53(16):6180-7
5-iodo-6-((2-iminoimidazolidinyl)methyl)uracil  0   Uracil/*analogs & derivatives. Nucl Med Biol. 2010 May;37(4):427-32
4-hydroxyborauracil  0   Uracil/*analogs & derivatives. Bioorg Chem. 2010 Feb;38(1):33-6
4-hydroxy-3-methylborauracil  0   Uracil/*analogs & derivatives. Bioorg Chem. 2010 Feb;38(1):33-6
1-(2-C-methyl-beta-D-ribofuranosyl)-uracil  0   Uracil/*analogs & derivatives. Nat Prod Commun. 2010 Feb;5(2):253-8
A 90289B  0   *Azepines Uracil/*analogs & derivatives. Chembiochem 2010 Jan 25;11(2):184-90
A 90289A  0   *Azepines Uracil/*analogs & derivatives. Chembiochem 2010 Jan 25;11(2):184-90
SMIFH2 compound  0   *Thiones Uracil/*analogs & derivatives. Chem Biol 2009 Nov 25;16(11):1158-68
AR C155858  0   *Thiophenes Uracil/*analogs & derivatives Monocarboxylic Acid Transporters/antagonists & inhibitors. Biochem J 2010 Feb 15;425(3):523-30
6-(2-aminoethyl)amino-5-chlorouracil  0   Uracil/*analogs & derivatives. Clin Cancer Res 2009 Aug 15;15(16):5136-44
6-amino-3-methyluracil-5-carbaldehyde  0   *Aldehydes Uracil/*analogs & derivatives. Acta Crystallogr C. 2009 Jun;65(Pt 6):o281-3
4-hydroxy-5,6-dihydroborauracil  0   Uracil/*analogs & derivatives. Bioorg Chem. 2009 Jun;37(3):65-9
4-methoxy-5,6-dihydroborauracil  0   Uracil/*analogs & derivatives. Bioorg Chem. 2009 Jun;37(3):65-9
4-bromo-5,6-dihydroborauracil  0   Uracil/*analogs & derivatives. Bioorg Chem. 2009 Jun;37(3):65-9
5,6-dihydrouracil 6-sulfonic acid  0   *Sulfonic Acids Uracil/*analogs & derivatives. Nucleic Acids Symp Ser (Oxf) 2008;(52):451-2
6-uracilmethylphosphonate  0   Uracil/*analogs & derivatives. Chemistry. 2008;14(32):10036-46
5-uracilmethylphosphonate  0   Uracil/*analogs & derivatives. Chemistry. 2008;14(32):10036-46
deoxymalayamicin A  0   *Pyrans Uracil/*analogs & derivatives. J Org Chem 2008 Nov 21;73(22):8929-41
2-(6-uradinyl)-4,4,5,5-tetramethyl-4,5-dihydro-1H-imidazole-1-oxyl  0   *Imidazoles Uracil/*analogs & derivatives. Chem Commun (Camb). 2008 Aug 7;(29):3441-3
3-(3,5-dimethylbenzyl)uracil  0   Uracil/*analogs & derivatives. Nucleosides Nucleotides Nucleic Acids. 2007;26(10-12):1553-8
6-chloro-5-cyclopent-1-en-1-yluracil  0   Uracil/*analogs & derivatives Thymidine Phosphorylase/antagonists & inhibitors. J Med Chem 2007 Nov 29;50(24):6016-23
betamecil  0   Uracil/*analogs & derivatives. Eksp Klin Farmakol 2007 Jul-Aug;70(4):7-10
1-(2-aminopyridin-4-ylmethyl)-6-(3,5-dimethylbenzoyl)-5-isopropyl-1H-pyrimidine-2,4-dione alanine amide  0   Alanine/*analogs & derivatives Uracil/*analogs & derivatives. J Vet Sci 2007 Sep;8(3):263-7
1-(2-aminopyridin-4-ylmethyl)-6-(3,5-dimethylbenzoyl)-5-isopropyl-1H-pyrimidine-2,4-dione  0   *Aminopyridines Uracil/*analogs & derivatives. J Vet Sci 2007 Sep;8(3):263-7
5,6-trimethyleneuracil  0   Uracil/*analogs & derivatives. Phys Chem Chem Phys 2007 Jul 7;9(25):3206-9
diaqua(5,5'-(pyridine-2,6-diylbis(methylidynenitrilo))bis(pyrimidine-2,4(1H,3H)-dione))zinc(II)  0   *Organometallic Compounds Uracil/*analogs & derivatives Zinc. Acta Crystallogr C 2007 Apr;63(Pt 4):m147-9
alogliptin  0   *Piperidines Uracil/*analogs & derivatives.
Pharma Action Dipeptidyl-Peptidase IV Inhibitors 		J Med Chem 2007 May 17;50(10):2297-300
5-(5',6'-benzocoumarin-3')-methylaminouracil hydrobromide  0   Uracil/*analogs & derivatives. Ukr Biokhim Zh 2006 Nov-Dec;78(6):86-92
1-(2-amino-2-carboxyethyl)-3-(2-carboxy-5-phenylthiophene-3-ylmethyl)-5-methylpyrimidine-2,4-dione  0   Alanine/*analogs & derivatives Uracil/*analogs & derivatives Receptors, Kainic Acid/antagonists & inhibitors. J Med Chem 2007 Apr 5;50(7):1558-70
1-(2-amino-2-carboxyethyl)-3-(2-carboxythiophene-3-ylmethyl)pyrimidine-2,4-dione  0   Alanine/*analogs & derivatives Uracil/*analogs & derivatives Receptors, Kainic Acid/antagonists & inhibitors. J Med Chem 2006 Apr 20;49(8):2579-92
4-(N-(2-(uracil-6-ylmethyliminooxy)ethyloxy)iminomethyl)benzoic acid  0   *Oximes Uracil/*analogs & derivatives. Nucleic Acids Res 2006;34(20):572-9
(4-(6-chloro-2,4-dioxo-1,2,3,4-tetrahydropyrimidin-5-yl)butyl) 1-phosphate  0   *Phosphoric Acid Esters Uracil/*analogs & derivatives. FEBS J 2006 Oct;273(20):4790-804
tunicaminyluracil  0   Uracil/*analogs & derivatives. Aust Vet J 1992 Sep;69(9):228-9
5-chlorocylindrospermopsin  0   Uracil/*analogs & derivatives. Angew Chem Int Ed Engl. 2005 Jun 20;44(25):3879-81
7-deoxycylindrospermopsin  0   Uracil/*analogs & derivatives. Angew Chem Int Ed Engl. 2005 Jun 20;44(25):3879-81
1-(2-deoxypentofuranosyl)isodialuric acid  0   Uracil/*analogs & derivatives. Nucleic Acids Res 2006;34(13):3660-9
6-(3,5-dimethylbenzyl)-1-(ethoxymethyl)-5-isopropyluracil  0   Uracil/*analogs & derivatives. J Med Chem 1999 Nov 4;42(22):4500-5
4-(1,3-dibenzyl-1,2,3,4-tetrahydro-2,4-dioxopyrimidin-5-yl)-2-hydroxy-4-oxobut-2-enoic acid  0   *Hydroxybutyrates Uracil/*analogs & derivatives. J Med Chem 2006 Jan 26;49(2):445-7
TEGAFOX protocol  0   Uracil *Antineoplastic Combined Chemotherapy Protocols Leucovorin Tegafur Organoplatinum Compounds. Br J Cancer. 2006 Jan 16;94(1):69-73
1-(2-amino-2-carboxyethyl)-3-(2-carboxybenzyl)-5-iodopyrimidine-2,4-dione  0   Alanine/*analogs & derivatives Uracil/*analogs & derivatives Receptors, Kainic Acid/antagonists & inhibitors. J Med Chem 2005 Dec 1;48(24):7867-81
5,6-benzocoumarin-5-uracil  0   *Coumarins Uracil/*analogs & derivatives. Ukr Biokhim Zh 2005 Mar-Apr;77(2):141-6
5-bromo-1-mesyluracil  0   *Sulfones Uracil/*analogs & derivatives. Nucleosides Nucleotides Nucleic Acids 2005;24(5-7):557-69
5-thiomethyluracil  0   Uracil/*analogs & derivatives. Org Lett 2005 Mar 3;7(5):751-4
ReCl(CO)3-6-amino-1,3-dimethyl-5-nitrosouracil  0   *Organometallic Compounds Uracil/*analogs & derivatives Rhenium. J Inorg Biochem. 2005 Aug;99(8):1637-45
5-fluoro-1-(6-O-acetyl-3,4-di-deoxy-3-fluoro-beta-D-glycero-hex-3-eno-pyranos-2-ulosyl) uracil  0   *Nucleosides Uracil/*analogs & derivatives. Nucleosides Nucleotides Nucleic Acids. 2005;24(4):243-6
5-fluoro-1,3-dimethyluracil  0   Uracil/*analogs & derivatives. Chem Pharm Bull (Tokyo). 2005 Feb;53(2):258-9
6-amino-1-methyl-5-nitrosouracil  0   *Nitroso Compounds Uracil/*analogs & derivatives. Spectrochim Acta A Mol Biomol Spectrosc. 2004 Nov;60(13):3093-100
TAS 102  0   *Trifluridine Drug Combinations Uracil/*analogs & derivatives. Int J Mol Med 2004 Apr;13(4):545-9
6-amino-1,3-dimethyl uracil  0   Uracil/*analogs & derivatives. Spectrochim Acta A Mol Biomol Spectrosc. 2003 Apr;59(6):1307-20
KIN-52  0   Uracil/*analogs & derivatives. Mol Pharmacol 2003 Feb;63(2):263-70
6-(3,5-dimethylbenzyl)-5-ethyl-1-(3-methylbut-2-enyloxymethyl)uracil  0   Uracil/*analogs & derivatives. J Med Chem 2002 Dec 19;45(26):5721-6
1-(allyloxymethyl)-6-(3,5-dimethylbenzyl)-5-ethyluracil  0   Uracil/*analogs & derivatives. J Med Chem 2002 Dec 19;45(26):5721-6
uracil-spyrodihydroindolizine  0   *Indolizines Uracil/*analogs & derivatives. J Photochem Photobiol B 2002 May;67(1):18-22
5-iodo-1-(4-thio-arabinofuranosyl)uracil  0   *Monosaccharides Uracil/*analogs & derivatives Tomography, Emission-Computed, Single-Photon. J Nucl Med 2002 Sep;43(9):1218-26
Agent No. 547  0   Uracil/*analogs & derivatives. Arch Toxicol 2002 Mar;76(2):122-6
6'-(5-carboxy-1,4-dimethyl-3-oxo-2H,3H-1,4-diazepin-2-yl)uracil  0   *Azepines Uracil/*analogs & derivatives. Org Lett 2002 Feb 21;4(4):603-6
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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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