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Tegafur
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Definition
: Congener of FLUOROURACIL with comparable antineoplastic action. It has been suggested especially for the treatment of breast neoplasms.
Pharmacological Action
Antimetabolites, Antineoplastic
Other names
FT 207; Bristol Myers Squibb Brand of Tegafur; Utefos; Uftoral; Sunfural S; Prasfarma Brand of Tegafur; N1-
(2'-
Tetrahydrofuryl)-
5-
fluorouracil; Futraful; Ftorafur; Fluorofur; Florafur; FT207; FT-
207; Bristol-
Myers Squibb Brand of Tegafur; Almirall Brand of Tegafur; 5-
Fluoro-
1-
(tetrahydro-
2-
furanyl)-
2,4-
pyrimidinedi; 1-
(Tetrahydro-
2-
furanyl)-
5-
fluorouracil; 1-
(2-
Tetrahydrofuryl)-
5-
fluorouracil
Substance
CAS Registry & name
Categories
Source
Drugs
*
FCD combination
0
*Tegafur
*Pyridines.
Toxicology 2006 Jan 16;217(2-3):233-9
TEGAFOX protocol
0
Uracil
*Antineoplastic Combined Chemotherapy Protocols
Leucovorin
Tegafur
Organoplatinum Compounds.
Br J Cancer. 2006 Jan 16;94(1):69-73
UFT(R) drug
0
*Tegafur
*Uracil
Drug Combinations.
Pharma Action
Antineoplastic Agents
Dig Dis Sci 1995 Nov;40(11):2434-7
FP protocol
0
Uracil
*Antineoplastic Combined Chemotherapy Protocols
Cisplatin
Tegafur.
Gan To Kagaku Ryoho 1995 Mar;22(4):515-20
S 1 (combination)
150863-82-4
*Tegafur
*Oxonic Acid
Drug Combinations.
Pharma Action
Antimetabolites, Antineoplastic
Gan To Kagaku Ryoho 1993 Jan; 20(1):10-18
VAU regimen
0
*Antineoplastic Combined Chemotherapy Protocols
Doxorubicin
Tegafur
Uracil
Vinblastine.
Cancer Chemother Pharmacol 1992;30(6):477-9
MVMF protocol
0
*Antineoplastic Combined Chemotherapy Protocols
Tegafur
Methotrexate
Vincristine
Mitomycin.
Jpn J Clin Oncol 1991;21(5):334
PMUE protocol
0
Uracil
*Antineoplastic Combined Chemotherapy Protocols
Cisplatin
Etoposide
Tegafur
Mitomycin.
Gan To Kagaku Ryoho 1990;17(12):2381
FEPA protocol
0
*Antineoplastic Combined Chemotherapy Protocols
Cisplatin
Doxorubicin
Etoposide
Tegafur
Uracil.
Gan To Kagaku Ryoho 1989;16(10):3393
COPU protocol
0
Uracil
*Antineoplastic Combined Chemotherapy Protocols
Cisplatin
Cyclophosphamide
Tegafur
Vincristine.
Chung Hua Chung Liu Tsa Chih 1989;11(1):47
BMFt protocol
0
*Antineoplastic Combined Chemotherapy Protocols
Bleomycin
Tegafur
Methotrexate.
Eur J Gynaecol Oncol 1989;10(4):271
CMU protocol
0
Tegafur
*Antineoplastic Combined Chemotherapy Protocols
Cyclophosphamide
Methotrexate
Uracil/analogs & derivatives.
Cancer 1989;63(9):1668
FAP regimen
0
*Antineoplastic Combined Chemotherapy Protocols
Cisplatin
Doxorubicin
Tegafur
Uracil.
Gan To Kagaku Ryoho 1988;15(11):3073
FEP protocol
0
Tegafur
*Antineoplastic Combined Chemotherapy Protocols
Cisplatin
Etoposide
Uracil.
Gan To Kagaku Ryoho 1988;15(11):3073
MQF-
OK-
FT protocol
0
*Antineoplastic Combined Chemotherapy Protocols
Carbazilquinone
Fluorouracil
Tegafur
Picibanil
Mitomycin.
Gan To Kagaku Ryoho 1988;15(7):2065
MQF-
OK-
UFT protocol
0
*Antineoplastic Combined Chemotherapy Protocols
Carbazilquinone
Fluorouracil
Tegafur
Mitomycins
Picibanil
Uracil.
Gan To Kagaku Ryoho 1988;15(7):2065
ACFT protocol
0
*Antineoplastic Combined Chemotherapy Protocols
Cyclophosphamide
Doxorubicin
Tegafur
Tamoxifen.
Gan To Kagaku Ryoho 1988;15(5):1711
PMU protocol
0
Uracil
*Antineoplastic Combined Chemotherapy Protocols
Cisplatin
Tegafur
Mitomycin.
Gan To Kagaku Ryoho 1988;15(4 Pt 1):655
ACFM protocol
0
*Antineoplastic Combined Chemotherapy Protocols
Cyclophosphamide
Doxorubicin
Tegafur
Methotrexate.
Cancer Chemother Pharmacol 1984;13(2):95
ACF protocol
0
*Antineoplastic Combined Chemotherapy Protocols
Cyclophosphamide
Doxorubicin
Tegafur.
Cancer Chemother Pharmacol 1984;13(2):95
UFTM protocol
0
Uracil
Tegafur
*Antineoplastic Combined Chemotherapy Protocols
Mitomycin.
Gan To Kagaku Ryoho 1984;11(3 pt 2):769
FAM II protocol
0
*Antineoplastic Combined Chemotherapy Protocols
Doxorubicin
Tegafur
Mitomycin.
Jpn J Clin Oncol 1984;14(1):3
FACP protocol
0
*Antineoplastic Combined Chemotherapy Protocols
Cisplatin
Cyclophosphamide
Doxorubicin
Tegafur.
J Clin Oncol 1984;2(3):207
AFC regimen
0
*Antineoplastic Combined Chemotherapy Protocols
Cytarabine
Doxorubicin
Tegafur.
Cancer Chemother Pharmacol 1983;11 Suppl:S89
UFD 1 protocol
0
*Antineoplastic Combined Chemotherapy Protocols
Tegafur/analogs & derivatives
Uracil.
Gan To Kagaku Ryoho 1982;9(4):674
1-
UFT protocol
0
Uracil
*Antineoplastic Combined Chemotherapy Protocols
Tegafur.
Arzneimittelforsch 1981;31(8):1268
dehydroftorafur
68723-23-9
Tegafur/*analogs & derivatives.
Cancer Treat Rep 1981;65(1-2):69
3-
FT
63901-83-7
*Tegafur
Isomerism.
J Chromatogr 1980;188(1):270
FD 1
62987-05-7 5-
fluoro-
1,3-
bis(tetrahydro-
2-
furanyl)-
2,4(1H,3H)-
pyrimidinedione
Tegafur/*analogs & derivatives.
J Chromatogr 157:321;1978; J Med Chem 21(8):738;1978; J Pharm Soc Jpn 98(4):525;1978; JNCI 63(2):456;1979; Nippon Gan Chiryo Gakkai Shi 14(2):129;1979; Recent Results Cancer Res 1980;70;133