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Indolequinones

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Definition: INDOLES which have two keto groups forming QUINONES like structures of the indole aromatic ring.  coord with appropriate specific chemical terms if pertinent   
Examples Mitomycins; Pyrroloiminoquinones 		Other names Indole Quinones; Indoloquinones; Indole-Quinones
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
leucoisoprenochrome-o-semiquinone  0   *Indolequinones. Chem Res Toxicol. 2004 Dec;17(12):1584-90
cysteine tryptophylquinone  0   *Dipeptides *Indolequinones. J Biol Chem 2002 Jan 25;277(4):2385-952830-4
5-methoxy-1,2-dimethyl-3-((4-nitrophenoxy)methyl)indole-4,7-dione  0   *Indolequinones NAD(P)H Dehydrogenase (Quinone). Biochemistry 2001 Dec 18;40(50):15135-42
2,5-dihydroxy-3-(1-methylindol-3-yl)-6-phenyl-1,4-benzoquinone  0   *Benzoquinones *Indolequinones. Nippon Rinsho 2001 Nov;59(11):2239-44
1,2,8,8a-tetrahydrocyclopropa(c)pyrrolo(3,2-e)indol-4(5H)-one  0   *Quinolones *Indolequinones. J Org Chem 2000 Jun 30;65(13):4101-11
aminochrome 1  39984-17-3   *Indolequinones. J Neurochem 1995 Feb;64(2):919-24
noradrenochrome  490-89-1   *Indolequinones. Biochim Biophys Acta 1994 Jul 6;1200(2):197-204
EO 5A  131610-90-7   *Indolequinones. J Chromatogr 1993 Jun 2;615(2):309-15
5-hydroxytryptamine-4,7-dione  100513-78-8   *Indolequinones 5,7-Dihydroxytryptamine/*analogs & derivatives Neurotoxins. J Med Chem 1993 Jan 22;36(2):229-36
tryptophan tryptophylquinone  134645-25-3 (2,4'-Bi-1H-indole)-3,3'-dipropanoic acid, alpha,alpha'-diamino-6',7'-dihydro-6',7'-dioxo  *Indolequinones Tryptophan/*analogs & derivatives. FEBS Lett 1991;287(1-2):163
quinone methide  138230-21-4   *Indolequinones. J Biol Chem 1991;266(10):6073
apaziquone  114560-48-4 1H-Indole-4,7-dione, 5-(1-aziridinyl)-3-(hydroxymethyl)-2- ((1E)-3-hydroxy-1-propenyl)-1-methyl  *Aziridines *Indolequinones.
Pharma Action Antineoplastic Agents 		Eur J Cancer Clin Oncol 1989;25(8):1197
tryptamine-4,5-dione  108560-71-0   *Tryptamines *Indolequinones. J Pharmacol Exp Ther 1989;250(1):141
4-(7'-(tryptamine-4,5-dione))-2,4''-bis-5-hydroxytryptamine  118230-91-4   *Indolequinones Serotonin/*analogs & derivatives. J Pharm Sci 1988;77(11):911
6,6-dimethyl-2-erythrofuranosyl-4,5,6,7-tetrahydroindol-4-one  91679-36-6 4H-Indol-4-one, 2-(2-deoxy-D-erythro-pentofuranosyl)-1,5,6,7-tetrahydro-6,6-dimethyl-, (S-(R*,R*))  *Nucleosides *Indolequinones. Methods Find Exp Clin Pharmacol 1984;6(5):241
6,6-dimethyl-2-beta-lyxopyranosyl-4,5,6,7-tetrahydroindol-4-one  0   *Nucleosides *Indolequinones. Sangre (Barc) 1980;25(2):153
indole-4,7-dione  20342-64-7   *Indolequinones. Yakugaku Zasshi 1979;99(12):1219
iprazochrome  7248-21-7 2-(1,2,3,6-tetrahydro-3-hydroxy-1-(1-methylethyl)-6-oxo-5H-indol-5-ylidene)hydrazinecarboxamide  *Indolequinones Adrenochrome/*analogs & derivatives.
Pharma Action Serotonin Antagonists 		Acta Neurol Scand 56:17;1977; Farmakol Toksikol 38(1):49;1975; Headache 18(4):225;1978; Headache 19(4):219;1979; Pharmacol Res Commun 9:587;1977
dopachrome  3571-34-4   *Indolequinones. Biochem Pharm 25(5):533;1976

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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