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Tranylcypromine

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Definition: A propylamine formed from the cyclization of the side chain of amphetamine. This monoamine oxidase inhibitor is effective in the treatment of major depression, dysthymic disorder, and atypical depression. It also is useful in panic and phobic disorders. (From AMA Drug Evaluations Annual, 1994, p311)     
Pharmacological Action Anti-Anxiety Agents; Antidepressive Agents; Monoamine Oxidase Inhibitors 		Other names trans 2 Phenylcyclopropylamine; Sulfate, Tranylcypromine; trans-2-Phenylcyclopropylamine; esparma Brand of Tranylcypromine Sulfate; Transamine; SmithKline Brand of Tranylcypromine Sulfate; Tranylcypromine Sulfate; Parnate; Link Brand of Tranylcypromine Sulfate; Jatrosom; Goldshield Brand of Tranylcypromine Sulfate; GlaxoSmithKline Brand of Tranylcypromine Sulfate; Allphar Brand of Tranylcypromine SulfateDrugs* : PARNATE; TRANYLCYPROMINE SULFATE
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
tranylcypromine-FA4  0   Tranylcypromine/*analogs & derivatives. Biochem Pharmacol. 2009 Dec 1;78(11):1412-7
2-fluoro-2-phenylcyclopropylamine  0   Tranylcypromine/*analogs & derivatives Monoamine Oxidase/antagonists & inhibitors. J Med Chem 2004 Mar 25;47(7):1796-806
4-methoxytranylcypromine  19009-68-8   Tranylcypromine/*analogs & derivatives. J Neural Transm Suppl 1990;32:107
4-fluorotranylcypromine  113516-71-5   Tranylcypromine/*analogs & derivatives. Cell Mol Neurobiol 1987;7(3):271
dichlorobis(tranylcypromine)platinum(II)  84152-26-1   Cisplatin/*analogs & derivatives Tranylcypromine/*analogs & derivatives. J Parasitol 1987;73(2):272
4-hydroxytranylcypromine  104777-77-7   Tranylcypromine/*analogs & derivatives. J Neural Transm 1986;65(3-4):233
N-2-cyanoethyltranylcypromine  95596-55-7   Tranylcypromine/*analogs & derivatives. Prog Neuropsychopharmacol Biol Psychiatry 1984;8(4-6):657
N-acetyl-tranylcypromine  38954-41-5   Tranylcypromine/*analogs & derivatives. Biochem Pharmacol 1981;30(8):861
LY 54761  18381-60-7 Ethanone, 2-(cyclopropylamino)-1-phenyl  Tranylcypromine/*analogs & derivatives. Biochem Pharmacol 27(18):2255;1978
ASL 7003  67035-23-8   Tranylcypromine/*analogs & derivatives. J Pharm Pharmacol 30(3):193;1978

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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