Definition: Alkaloid isolated from seeds of Peganum harmala L., Zygophyllaceae. It is identical to banisterine, or telepathine, from Banisteria caapi and is one of the active ingredients of hallucinogenic drinks made in the western Amazon region from related plants. It has no therapeutic use, but (as banisterine) was hailed as a cure for postencephalitic Parkinson disease in the 1920's.
Anal Biochem 92(2):331;1979; Biochem Biophys Res Commun 79(4):1167;1977; Biochem Biophys Res Commun 83(2):373;1978; Cancer Res 38(12):4527;1978; J Nat Prod 38(2):125;1975; Mutat Res 58(2-3):151;1978; Nucleic Acids Res 4(11):3679;1977; Proc Natl Acad Sci USA 75(2):928;1978
Biochem Biophys Res Commun 79(4):1167;1977; Cancer Res 38(12):4527;1978; FEBS Lett 1980;109(2):1209; J Nat Prod 38(2):125;1975; Nucleic Acids Res 4(11):3679;1977; Proc Natl Acad Sci USA 75(2):928;1978