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nitrocefin

under Cephalosporins
More information in Books or onNLM PubMed
More on Cephalosporins Definition: A group of broad-spectrum antibiotics first isolated from the Mediterranean fungus ACREMONIUM. They contain the beta-lactam moiety thia-azabicyclo-octenecarboxylic acid also called 7-aminocephalosporanic acid.      Other names Antibiotics, Cephalosporin; Cephalosporin Antibiotics; Acids, Cephalosporanic; Cephalosporanic Acids
SubstanceCAS Registry & nameCategoriesSourceDrugs*
nitrocefin [ Cefinase,glaxo 87-312,nitrocefin, (6R-trans)-isomer,nitrocefin, monosodium salt,nitrocefin, sodium salt, (6R-trans)-isomer ]
  chromogenic cephalosporin used for detection of beta-lactamase activity; Cefinase is name for nitrocefin on paper disc; RN given refers to (6R-(3(E),6 alpha,7 beta))-isomer; structure for mono-Na salt 		41906-86-9 (6R-(3(E),6 alpha,7 beta))-3-(2-(2,4-dinitrophenyl)ethenyl)-8-oxo-7-((2-thienylacetyl)amino)- 5-thia-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylic acid  *Cephalosporins
Pharma Action Indicators and Reagents 		Antimicrob Ag Chemother 10(3):470;1976; J Clin Microbiol 9(6):654;1979

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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