encyclopedia of medical concepts
ψ
lofexidine
under Clonidine
More information
in Books
or on
More on
Clonidine
Definition
: An imidazoline sympatholytic agent that stimulates ALPHA-2 ADRENERGIC RECEPTORS and central IMIDAZOLINE RECEPTORS. It is commonly used in the management of HYPERTENSION.
Other names
ST155; ST 155; Monohydrochloride, Clonidine; Monohydrobromide, Clonidine; M5041T; M 5041T; Hydrochloride, Clonidine; Dihydrochloride, Clonidine; ST-
155; M-
5041T; Klofenil; Klofelin; Isoglaucon; Hemiton; Gemiton; Dixarit; Clopheline; Clonidine Monohydrochloride; Clonidine Monohydrobromide; Clonidine Hydrochloride
Drugs:
KAPVAY
JENLOGA
;
CLONIDINE
;
CATAPRES-TTS-1
;
CATAPRES-TTS-2
;
CATAPRES
;
CATAPRES-TTS-3
;
CLONIDINE HYDROCHLORIDE
;
DURACLON
;
Substance
CAS Registry & name
Categories
Source
Drugs
*
lofexidine [ BritLofex,2-(alpha-(2,6-dichlorophenoxy)ethyl) delta-2-imidazoline,Britannia Brand of Lofexidine Monohydrochloride,Lofexidine mono-hydrochloride,lofexidine hydrochloride,lofexidine monohydrochloride,lofexidine, (+-)-isomer ]
reduces narcotic withdrawal symptoms; RN given refers to parent cpd without isomeric designation; structure in Negwer, 5th ed, #6247
31036-80-3 1H-
imidazole, 2-
(1-
(2,6-
dichlorophenoxy)ethyl)-
4,5-
dihydro
Clonidine/*analogs & derivatives
Pharma Action
Antihypertensive Agents
;
Narcotic Antagonists
;
Adrenergic alpha-2 Receptor Agonists
Pharmacol Biochem Behav 1980;12(4):573
