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2-amino-7-phosphonoheptanoic acid

under 2-Amino-5-phosphonovalerate
More information in Books or onNLM PubMed
More on 2-Amino-5-phosphonovalerate Definition: The D-enantiomer is a potent and specific antagonist of NMDA glutamate receptors (RECEPTORS, N-METHYL-D-ASPARTATE). The L form is inactive at NMDA receptors but may affect the AP4 (2-amino-4-phosphonobutyrate; APB) excitatory amino acid receptors.      Other names 2 Amino 5 phosphonopentanoate; dl-APV; d-APV; 5-Phosphononorvaline; 2-Amino-5-phosphonopentanoate; 2-Amino-5-phosphonovaleric Acid; 2-Amino-5-phosphonopentanoic Acid; 2-APV; 5 Phosphononorvaline; 2 Amino 5 phosphonovaleric Acid; 2 Amino 5 phosphonovalerate; 2 Amino 5 phosphonopentanoic Acid
SubstanceCAS Registry & nameCategoriesSourceDrugs*
2-amino-7-phosphonoheptanoic acid [ 2-amino-7-phosphoheptanoic acid,2-amino-7-phosphonoheptanoic acid, (+-)-isomer,2-amino-7-phosphonoheptanoic acid, (R)-isomer,D-AP7,2-amino-7-phosphonoheptanoic acid, (S)-isomer,AP-7 compound ]
  (D)-isomer active as an antagonist of N-methyl-D-aspartate excitation of central neurons; (L)-isomer inactive; RN given refers to cpd without isomeric designation 		85797-13-3 Heptanoic acid, 2-amino-7-phosphono-, (+-)  2-Amino-5-phosphonovalerate/*analogs & derivatives
Pharma Action Anticonvulsants; Excitatory Amino Acid Antagonists 		Neurosci lett 1981;23(3):333

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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