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plomestane

under Androstenedione
More information in Books or onNLM PubMed
More on Androstenedione Definition: A delta-4 C19 steroid that is produced not only in the TESTIS, but also in the OVARY and the ADRENAL CORTEX. Depending on the tissue type, androstenedione can serve as a precursor to TESTOSTERONE as well as ESTRONE and ESTRADIOL.  note double bond at the C4 position; do not confuse with androstanedione which is without the double bond    Other names delta 4 Androstenedione; 4 Androstene 3,17 dione; delta-4-Androstenedione; 4-Androstene-3,17-dione
SubstanceCAS Registry & nameCategoriesSourceDrugs*
plomestane [ 10-PED,10-propargylandrost-4-ene-3,17-dione,10-propargylestr-4-ene-3,17-dione,19-acetylenic androstenedione,MDL 18962,MDL-18,962 ]
  selective inhibitor of aromatization in human breast tissue; may provide a mechanism for controlling estrogen responsive processes
77016-85-4 Estr-4-ene-3,17-dione, 10-(2-propynyl)  Androstenedione/*analogs & derivatives Pargyline/*analogs & derivatives
Pharma Action Antineoplastic Agents; Aromatase Inhibitors
Steroids 1981;38(4):397

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012

Warning: the drugs or drug combinations referred to here may be similar or related, but are not be the same ones and may not have the same pharmacological action as other substances described on the same page or in the same row. Please refer to product monograph or to your doctor
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