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MMC protein, Momordica charantia

under Ribosome Inactivating Proteins
More information in Books or onNLM PubMed
More on Ribosome Inactivating Proteins Definition: N-Glycosidases that remove adenines from RIBOSOMAL RNA, depurinating the conserved alpha-sarcin loop of 28S RIBOSOMAL RNA. They often consist of a toxic A subunit and a binding lectin B subunit. They may be considered as PROTEIN SYNTHESIS INHIBITORS. They are found in many PLANTS and have cytotoxic and antiviral activity.      Other names rRNA N Glycosylases; RNA N Glycosidase; Proteins, Ribosome Inactivating; N-Glycosylases, rRNA; N-Glycosidase, RNA; Inactivating Proteins, Ribosome; Glycosylase, RNA; Glycosidase, Polynucleotide Adenosine; Adenosine Glycosidase, Polynucleotide; rRNA N-Glycosylases; RNA Glycosylase; RIP (Ribosome Inactivating Proteins); Polynucleotide Adenosine Glycosidase; RNA N-Glycosidase
SubstanceCAS Registry & nameCategoriesSourceDrugs*
MMC protein, Momordica charantia [ Alpha-MMC protein, Momordica charantia,Beta-MMC protein, Momordica charantia,alpha-momorcharin,beta-momorcharin,momorcharin ]
  basic glycoprotein MW 31,000 isolated from seeds of Momordica charantia; ribosome inactivating protein 		88026-31-7   *Ribosome Inactivating Proteins
Pharma Action Abortifacient Agents, Nonsteroidal; Antineoplastic Agents, Phytogenic 		J Reprod Fertil 1983;69(2):597

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