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combretastatin

under Bibenzyls
More information in Books or onNLM PubMed
More on Bibenzyls Definition: Compounds with 1,2-diphenylethane. They are structurally like reduced STILBENES.     
SubstanceCAS Registry & nameCategoriesSourceDrugs*
combretastatin [ 3-hydroxy-4-methoxy-alpha-(3,4,5-trimethoxyphenyl)benzeneethanol,NSC 348103,NSC-348103 ]
  cytotoxic principle from South African tree COMBRETUM caffrum; structure given in first source; acts at COLCHICINE site of TUBULIN
82855-09-2   *Bibenzyls Combretum
Pharma Action Antineoplastic Agents, Phytogenic; Tubulin Modulators
Biochem Pharmacol 1983;32(24):3864

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012

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