Definition: Aminoacridine derivative that is a potent intercalating antineoplastic agent. It is effective in the treatment of acute leukemias and malignant lymphomas, but has poor activity in the treatment of solid tumors. It is frequently used in combination with other antineoplastic agents in chemotherapy protocols. It produces consistent but acceptable myelosuppression and cardiotoxic effects.
Other names m-AMSA; meta AMSA; SN 11841; NSC249992; NSC156303; NSC141549; NSC 249992; NSC 156303; NSC 141549; Cains Acridine; Cain Acridine; Amsacrine G+¦decke Brand; Acridine, Cain's; AMSA PD; AMSA P D; meta-AMSA; SN11841; SN-11841; Parke Davis Brand of Amsacrine Lactate; Parke Davis Brand of Amsacrine
asulacrine [ 4-Acridinecarboxamide, 9-((2-methoxy-4-((methylsulfonyl)amino)phenyl)amino)-N,5-dimethyl-,CI 921,CI-921,N-5-dimethyl-9-((2-methoxy-4-methylsulfonylamino)phenylamino)-4-acridinecarboxamide,NSC 343499,NSC-343499 ] derivative of amsacrine; structure given in first source
