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bryostatin 1

under Bryostatins
More information in Books or onNLM PubMed
More on Bryostatins Definition: A group of 20-member macrolactones in which there are three remotely substituted pyran rings that are linked by a methylene bridge and an E-disubstituted alkene, and have geminal dimethyls at C8 and C18 carbons. Some interact with PROTEIN KINASE C.     
SubstanceCAS Registry & nameCategoriesSourceDrugs*
bryostatin 1
  a protein kinase C activator; macrocyclic lactone from marine Bryozoan Bugula neritina; RN given refers to (1S*-(1R*,3R*,5Z,7S*,8E,11R*,12R*(2E,4E),13E,15R*,17S*(S*),21S*,23S*,25R*))-isomer; structure 		83314-01-6   *Bryostatins Enzyme Activation Mitogens
Pharma Action Adjuvants, Immunologic; Antineoplastic Agents 		Biochem Biophys Res Commun 1985;131(3):1109

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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