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pegademase bovine

under Adenosine Deaminase
More information in Books or onNLM PubMed
More on Adenosine Deaminase Definition: An enzyme that catalyzes the hydrolysis of ADENOSINE to INOSINE with the elimination of AMMONIA.  /defic: consider also SEVERE COMBINED IMMUNODEFICIENCY or SCID    Other names Adenosine Aminohydrolase; Deaminase, Adenosine; Aminohydrolase, Adenosine
SubstanceCAS Registry & nameCategoriesSourceDrugs*
pegademase bovine [ PEG-ADA,pegADA,pegademase,polyethylene glycol-modified adenosine deaminase ]
  polyethylene glycol covalently attached to adenosine deaminase; used to stabilize the enzyme for therapy of adenosine deaminase deficiency and severe combined immunodeficiency disease 		EC 3.5.4.-   *Adenosine Deaminase Drug Carriers Severe Combined Immunodeficiency N Engl J Med 1987;316(10):589 ADAGEN

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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