encyclopedia of medical concepts
ψ

2-hydroxysaclofen

under Baclofen
More information in Books or onNLM PubMed
More on Baclofen Definition: A GAMMA-AMINOBUTYRIC ACID derivative that is a specific agonist of GABA-B RECEPTORS. It is used in the treatment of MUSCLE SPASTICITY, especially that due to SPINAL CORD INJURIES. Its therapeutic effects result from actions at spinal and supraspinal sites, generally the reduction of excitatory transmission.      Other names Chlorophenyl GABA; Baclophen; PMSBaclofen; PMS Baclofen; NuBaclo; Nu Pharm Brand of Baclofen; Nu Baclo; GenBaclofen; Gen Baclofen; GABA, Chlorophenyl; Ciba Geigy Brand of Baclofen; CIBA34,647BA; Baclof+¿neIrex; Baclof+¿ne Irex; Baclofen Pharmascience Brand; Baclofen Nu-Pharm Brand; Baclofen Novartis Brand; Baclofen Medtronic Brand; Baclofen Isis Brand; Baclofen Irex Brand Drugs: LIORESALGABLOFEN; KEMSTRO; BACLOFEN;
SubstanceCAS Registry & nameCategoriesSourceDrugs*
2-hydroxysaclofen [ 2-OH-saclofen,2-hydroxy-saclofen,3-amino-2-(4-chlorophenyl)-2-hydroxypropylsulfonic acid ]
  structure given in first source 		117354-64-0 Benzeneethanesulfonic acid, beta-(aminomethyl)-4-chloro-beta-hydroxy  Baclofen/*analogs & derivatives
Pharma Action GABA-B Receptor Antagonists 		Neurosci Lett 1988;92(1):92

To share this definition, click "text" (Facebook, Twitter) or "link" (blog, mail) then paste text link
Ads by Google

Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
Warning: the drugs or drug combinations referred to here may be similar or related, but are not be the same ones and may not have the same pharmacological action as other substances described on the same page or in the same row. Please refer to product monograph or to your doctor
This website is accredited by Health On the Net Foundation. Click to verify. We comply with the HONcode standard for trustworthy health information: verify here.
About Reference.MD Privacy