Definition: A group of compounds that contain the structure SO2NH2. Members of this group, also known as sulfa drugs, are derivatives of sulfanilamide, which competitively inhibit folic acid synthesis in microorganisms, and are bacteriostatic. They have been largely supplanted by more effective and less toxic antibiotics. (From Dorland, 28th ed)
Other names Mixtures, Sulfonamide; Sulfonamide Mixtures
sezolamide [ MK 0927,(+-)-isomer of sezolamide,(R)-isomer of sezolamide,(S)-isomer of sezolamide,5,6-dihydro-4-(2-methylpropyl)amino-4H-thieno(2,3-b)thiopyran-2-sulfonamide-7,7-dioxide,MK 417,MK 927,MK-0927,MK-417,MK-927,sezolamide hydrochloride,sezolamide monohydrochloride,sezolamide monohydrochloride(+)-(S)-isomer ] decreases intraocular pressure, topically in vivo; inhibits carbonic anhydrase; RN given refers to parent cpd without isomeric designation