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Carbonic Anhydrase Inhibitors

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Definition: A class of compounds that reduces the secretion of H+ ions by the proximal kidney tubule through inhibition of CARBONIC ANHYDRASES.  DF: CARBONIC ANHYDRASE INHIB    Other names Carbonate Dehydratase Inhibitors; Inhibitors, Carbonic Anhydrase; Inhibitors, Carbonate Dehydratase; Inhibitors, Carboxyanhydrase; Carboxyanhydrase Inhibitors
Substances having this pharmacologic action: benzenesulfonamide; Dichlorphenamide; Methazolamide; Benzolamide; Acetazolamide; Ethoxzolamide; brinzolamide; dorzolamide; sezolamide
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
4-(4-((glucopyranosyl)thiomethyl)-5-iodo-1-H-1,2,3-triazol-1-yl)benzenesulfonamide  0   *Glucosides *Sulfonamides Carbonic Anhydrase Inhibitors. J Med Chem. 2011 Oct 13;54(19):6905-18.
4-(4-((2',3',4',6'-tetra-O-acetylglucopyranosyl)thiomethyl)-5-iodo-1-H-1,2,3-triazol-1-yl)benzenesulfonamide  0   *Glucosides *Sulfonamides Carbonic Anhydrase Inhibitors. J Med Chem. 2011 Oct 13;54(19):6905-18.
VII-20 monoclonal antibody  0   *Antibodies, Monoclonal Carbonic Anhydrase Inhibitors. J Immunol Methods. 2003 Nov;282(1-2):117-34

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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