Definition: A macrolide isolated from the culture broth of a strain of Streptomyces tsukubaensis that has strong immunosuppressive activity in vivo and prevents the activation of T-lymphocytes in response to antigenic or mitogenic stimulation in vitro.
Other names Tacrolimus, Anhydrous; FR900506; FR 900506; FK 506; Prograft; Prograf; Janssen Brand of Tacrolimus; Fujisawa Brand of Tacrolimus; FR-900506; Cilag Brand of Tacrolimus; Anhydrous Tacrolimus; FK-506; FK506