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immunomycin

under Tacrolimus
More information in Books or onNLM PubMed
More on Tacrolimus Definition: A macrolide isolated from the culture broth of a strain of Streptomyces tsukubaensis that has strong immunosuppressive activity in vivo and prevents the activation of T-lymphocytes in response to antigenic or mitogenic stimulation in vitro.      Other names Tacrolimus, Anhydrous; FR900506; FR 900506; FK 506; Prograft; Prograf; Janssen Brand of Tacrolimus; Fujisawa Brand of Tacrolimus; FR-900506; Cilag Brand of Tacrolimus; Anhydrous Tacrolimus; FK-506; FK506 Drugs: TACROLIMUSPROGRAF; PROTOPIC;
SubstanceCAS Registry & nameCategoriesSourceDrugs*
immunomycin [ FK 520,FK-520,FR 900520,FR-900520,ascomycin ]
  from Streptomyces hygroscopicus; structure given in first source 		104987-12-4 15,19-Epoxy-3H-pyrido(2,1-c)(1,4)oxaazacyclotricosine-1,7,20,21(4H,23H)-tetrone, 8-ethyl-5,6,8,11,12,13,14,15,16,17,18,19,24,25,26,26a-hexadecahydro-5,19-dihydroxy-3-(2-(4-hydroxy-3-methoxycyclohexyl)-1-methylethenyl)-14,16-dimethoxy-4,10,12,18-tetram  Tacrolimus/*analogs & derivatives
Pharma Action Anti-Bacterial Agents; Immunosuppressive Agents 		J Antibiot (Tokyo) 1988;41(11):1592

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