4'-N-benzoylstaurosporine (definition)

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4'-N-benzoylstaurosporine

under Staurosporine

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Definition: An indolocarbazole that is a potent PROTEIN KINASE C inhibitor which enhances cAMP-mediated responses in human neuroblastoma cells. (Biochem Biophys Res Commun 1995;214(3):1114-20)

Substance	CAS Registry & name	Categories	Source	Drugs*
4'-N-benzoylstaurosporine [ 4'-N-benzoyl staurosporine,CGP 41 251,CGP 41251,CGP-41251,benzoylstaurosporine,midostaurin ] structure given in first source; staurosporine analog	120685-11-2 Benzamide, N-(2,3,9,10,11,12-hexahydro-9-methoxy-8-methyl-1-oxo-8,12-epoxy-1H,8H-2,7b,12a-triazadibenzo(a,g)cyclonona(cde)trinden-10-yl)-N-methyl-, (8alpha,9beta,10beta,12alpha)	Staurosporine/analogs & derivatives Protein Kinase C/antagonists & inhibitors Pharma Action* Antineoplastic Agents; Enzyme Inhibitors	Int J Cancer 1989;43(5):851

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
Warning: the drugs or drug combinations referred to here may be similar or related, but are not be the same ones and may not have the same pharmacological action as other substances described on the same page or in the same row. Please refer to product monograph or to your doctor

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