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dolastatin 10

under Depsipeptides
More information in Books or onNLM PubMed
More on Depsipeptides Definition: Compounds consisting of chains of AMINO ACIDS alternating with CARBOXYLIC ACIDS via ester and amide linkages. They are commonly cyclized.      Other names Cyclic Depsipeptides; Depsipeptides, Cyclic; Cyclodepsipeptides; Cryptophycins
SubstanceCAS Registry & nameCategoriesSourceDrugs*
dolastatin 10 [ NSC 376128,Deo-Dola 10,deo-dolastatin 10,isodolastatin 10 ]
  from mollusk Dolabella auricularia; contains four amino acids, dolavaline, dolaisoleucine, dolaproine, valine and the primary amine dolaphenine; deo-dolastatin 10 is a new dolastatin 10 chiral derivat 		110417-88-4   *Depsipeptides
Pharma Action Antineoplastic Agents; Tubulin Modulators 		Biochem Pharmacol 1990;39(12):1941

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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