Definition: A group of diterpenoid CYCLODECANES named for the taxanes that were discovered in the TAXUS tree. The action on MICROTUBULES has made some of them useful as ANTINEOPLASTIC AGENTS.
docetaxel [ N-debenzoyl-N-tert-butoxycarbonyl-10-deacetyltaxol,NSC 628503,RP 56976,RP-56976,Taxoltere metro,Taxotere,docetaxel, isomer,docetaxol ] semisynthetic analog of taxol; structure given in first source; RN given refers to anhydrous compound; 148408-66-6 is the isomer (2aR-(2aalpha,4beta,4abeta,6beta,9alpha(alphaR*,betaS*),11alpha,12alpha