Definition: Cellular DNA-binding proteins encoded by the sis gene (GENES, SIS). c-sis proteins make up the B chain of PLATELET-DERIVED GROWTH FACTOR. Overexpression of c-sis causes tumorigenesis.
Other names sis, Proto-Oncogene Proteins; sis, Proto-Oncogene Protein; sis Proto Oncogene Proteins; Proto-Oncogene Proteins, sis; Proto Oncogene Proteins sis; Proto Oncogene Proteins c sis; Proto Oncogene Protein sis; Proto Oncogene Products c sis; Platelet Derived Growth Factor B; Proto-Oncogene Proteins sis; Proto-Oncogene Protein sis; c sis Proteins; Proto-Oncogene Products c-sis; sis Proto-Oncogene Proteins; c-sis Proteins; Platelet-Derived Growth Factor B; PDGFB
platelet-derived growth factor BB [ PDGF-BB,Janssen brand of becaplermin,Regranex,becaplermin,platelet-derived growth factor BB, recombinant,rPDGF-BB,recombinant platelet-derived growth factor BB,rhPDGF-BB ] dimer of the B chain of platelet-derived growth factor; used for angiogenesis stimulation for wounds; Becaplermine gel (Regranex) contains 100 microg of (rhPDGF-BB) per gram and is used as adjuvant tr