encyclopedia of medical concepts
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Proto-Oncogene Proteins c-sis
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Definition
: Cellular DNA-binding proteins encoded by the sis gene (GENES, SIS). c-sis proteins make up the B chain of PLATELET-DERIVED GROWTH FACTOR. Overexpression of c-sis causes tumorigenesis.
See Also
Genes, sis
Other names
sis, Proto-
Oncogene Proteins; sis, Proto-
Oncogene Protein; sis Proto Oncogene Proteins; Proto-
Oncogene Proteins, sis; Proto Oncogene Proteins sis; Proto Oncogene Proteins c sis; Proto Oncogene Protein sis; Proto Oncogene Products c sis; Platelet Derived Growth Factor B; Proto-
Oncogene Proteins sis; Proto-
Oncogene Protein sis; c sis Proteins; Proto-
Oncogene Products c-
sis; sis Proto-
Oncogene Proteins; c-
sis Proteins; Platelet-
Derived Growth Factor B; PDGFB
Substance
CAS Registry & name
Categories
Source
Drugs
*
platelet-
derived growth factor BB
0
*Proto-Oncogene Proteins c-sis
Anticoagulants
Recombinant Proteins.
Pharma Action
Angiogenesis Inducing Agents
Lancet 1992;339(8784):23
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