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RB 101

under Disulfides
More information in Books or onNLM PubMed
More on Disulfides Definition: Chemical groups containing the covalent disulfide bonds -S-S-. The sulfur atoms can be bound to inorganic or organic moieties.     
SubstanceCAS Registry & nameCategoriesSourceDrugs*
RB 101 [ RB101,N-(2-benzyl-3-((2-amino-4-methylthio)butyl dithio)-1-oxopropyl)phenylalanine benzyl ester,RB-101 ]
  structure given in first source; inhibits enkephalinase and aminopeptidases; biologically cleaved at disulfide to produce inhibitors of both aminopeptidase N and neutral endopeptidase
135949-60-9 L-Phenylalanine, N-(2-(((2-amino-4-(methylthio)butyl)dithio)methyl)-1-oxo-3-phenylpropyl)-, phenylmethyl ester  *Disulfides Phenylalanine/*analogs & derivatives Prodrugs
Pharma Action Analgesics; Enzyme Inhibitors
J Pharmacol Exp Ther 1992 Apr;261(1):181-90

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012

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