Definition: A family of structurally related neurotoxic peptides from mollusk venom that inhibit voltage-activated entry of calcium into the presynaptic membrane. They selectively inhibit N-, P-, and Q-type calcium channels.
Other names omega Conotoxins; omega Conotoxin; omega-Conotoxin
ziconotide [ Elan brand of omega-conopeptide MVIIA,Prialt,SNX 111,SNX-111,omega-conopeptide MVIIA,omega-conotoxin MVIIA,omega-conotoxin MVIIA, Conus magus ] amino acid sequence in first source; from venom of South Pacific sea cone snail, Conus magus; calcium channel blocker; administered by injection into Cerebrospinal Fluid; Prialt is synthetic form