encyclopedia of medical concepts
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GEM91

under Thionucleotides
More information in Books or onNLM PubMed
More on Thionucleotides Definition: Nucleotides in which the base moiety is substituted with one or more sulfur atoms.     
SubstanceCAS Registry & nameCategoriesSourceDrugs*
GEM91 [ GEM 91,gene expression modulator 91,trecovirsen ]
  a 25-mer antisense oligonucleotide phosphorothioate used as a therapeutic agents for AIDS; may block the translation of gag mRNA& disrupt the secondary structure of RNA 		0   *Thionucleotides
Pharma Action Anti-HIV Agents; Oligodeoxyribonucleotides, Antisense 		Antisense Res Dev 1992 Winter;2(4):261-6

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