Definition: Organic compounds which contain P-C-P bonds, where P stands for phosphonates or phosphonic acids. These compounds affect calcium metabolism. They inhibit ectopic calcification and slow down bone resorption and bone turnover. Technetium complexes of diphosphonates have been used successfully as bone scanning agents.
zoledronic acid [ 2-(imidazol-1-yl)-1-hydroxyethylidene-1,1-bisphosphonic acid,CGP 42'446,CGP 42446A,CGP-42'446,CGP-42446,Novartis brand of zoledronic acid,Zometa,zoledronate ] a potent inhibitor of bone resorption; structure given in first source