Definition: Antibodies from non-human species whose protein sequences have been modified to make them nearly identical with human antibodies. If the constant region and part of the variable region are replaced, they are called humanized. If only the constant region is modified they are called chimeric. INN names for humanized antibodies end in -zumab.
Other names Humanized Antibodies; Antibodies, Humanized
alemtuzumab [ Berlex brand of alemtuzumab,Campath,Campath 1G,Campath 1H,Campath 1M,Campath-1-G,Campath-1G,Campath-1H,Campath-1M,MabCambath,MedacSchering brand of alemtuzumab,Schering brand of alemtuzumab,monoclonal antibody Campath-1H ] a therapeutic antibody directed against the CD52 antigen expressed by the lymphocytes and has proven lytic abilities both in vitro & in vivo