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FTI 277
under Methionine
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Methionine
Definition
: A sulfur containing essential amino acid that is important in many body functions. It is a chelating agent for heavy metals.
/biosyn /defic /physiol permitted
Other names
Methionine, L Isomer; Methionine, DL Isomer; L-
Isomer Methionine; DL-
Isomer Methionine; Racemethionine; Pedameth; Methionine, L-
Isomer; Methionine, DL-
Isomer; Liquimeth; L-
Methionine
Substance
CAS Registry & name
Categories
Source
Drugs
*
FTI 277 [ FTI-277 ]
a ras CAAX (C - Cys; A - aliphatic amino acid; X - Ser or Met) peptidomimetic; inhibits farnesyltransferase; blocks Ras oncogenic signaling by accumulating Ras/Raf complexes in the cytoplasm; structur
0
Methionine/*analogs & derivatives
Pharma Action
Enzyme Inhibitors
;
Radiation-Sensitizing Agents
J Biol Chem 1995 Nov 10;270(45):26802-6