encyclopedia of medical concepts
ψ
ψ
ψ
ψ

FTI 277

under Methionine
More information in Books or onNLM PubMed
More on Methionine Definition: A sulfur containing essential amino acid that is important in many body functions. It is a chelating agent for heavy metals.  /biosyn /defic /physiol permitted    Other names Methionine, L Isomer; Methionine, DL Isomer; L-Isomer Methionine; DL-Isomer Methionine; Racemethionine; Pedameth; Methionine, L-Isomer; Methionine, DL-Isomer; Liquimeth; L-Methionine
SubstanceCAS Registry & nameCategoriesSourceDrugs*
FTI 277 [ FTI-277 ]
  a ras CAAX (C - Cys; A - aliphatic amino acid; X - Ser or Met) peptidomimetic; inhibits farnesyltransferase; blocks Ras oncogenic signaling by accumulating Ras/Raf complexes in the cytoplasm; structur 		0   Methionine/*analogs & derivatives
Pharma Action Enzyme Inhibitors; Radiation-Sensitizing Agents 		J Biol Chem 1995 Nov 10;270(45):26802-6

To share this definition, click "text" (Facebook, Twitter) or "link" (blog, mail) then paste text link
Ads by Google

Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
Warning: the drugs or drug combinations referred to here may be similar or related, but are not be the same ones and may not have the same pharmacological action as other substances described on the same page or in the same row. Please refer to product monograph or to your doctor
This website is accredited by Health On the Net Foundation. Click to verify. We comply with the HONcode standard for trustworthy health information: verify here.
About Reference.MD Privacy