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CNI 1493

under Hydrazones
More information in Books or onNLM PubMed
More on Hydrazones Definition: Compounds of the general formula R:N.NR2, as resulting from the action of hydrazines with aldehydes or ketones. (Grant & Hackh's Chemical Dictionary, 5th ed)  do not confuse with HYDRAZINES   
SubstanceCAS Registry & nameCategoriesSourceDrugs*
CNI 1493 [ CNI-1493,N,N'-bis(3,5-diacetylphenyl)decanediamide tetrakis(amidinohydrazone) tetrahydrochloride,semapimod ]
  macrophage-deactivating agent used to treat experimental autoimmune encephalomyelitis in mice; a tetravalent guanylhydrazone; structure given in first source
0   *Hydrazones Cytokines/antagonists & inhibitors
Pharma Action Anti-Inflammatory Agents, Non-Steroidal; Immunosuppressive Agents
Mol Med 1995 Mar;1(3):254-66

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012

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