Definition: Nucleotide sequences, generated by iterative rounds of SELEX APTAMER TECHNIQUE, that bind to a target molecule specifically and with high affinity.
Other names RNA Oligonucleotide Ligands; DNA Oligonucleotide Ligands; Aptamers, RNA; Oligonucleotide Ligands, RNA; Oligonucleotide Ligands, DNA; Nucleotide Aptamers; Aptamers, DNA; RNA Aptamers; DNA Aptamers
pegaptanib [ Macugen ] a 28-base ribonucleic acid aptamer covalently linked to two branched 20-kD polyethylene glycol moieties to block the activity of extracellular VEGF, specifically the 165-amino-acid isoform (VEGF165);