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Apamin

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Definition: A highly neurotoxic polypeptide from the venom of the honey bee (Apis mellifera). It consists of 18 amino acids with two disulfide bridges and causes hyperexcitability resulting in convulsions and respiratory paralysis.  a bee venom; /antag permitted but consider also ANTIVENINS; do not confuse with drug Apamide (   
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
4-azido-2-nitrophenylaminoacetylmonoiodoapamin  96518-36-4 Apamin, N-(N-(4-azido-2-nitrophenyl)glycyl)-18-((iodo-125I)-L-histidinamide)-, (R)  *Azides Apamin/*analogs & derivatives. J Biol Chem 1985;260(7):3895
monoiodoapamin  70592-40-4 Apamin, 18-(iodo-125I-L-histidinamide)  Apamin/*analogs & derivatives. J Biol Chem 1982;257(6):2762
apamin receptor  0   *Potassium Channels Apamin. J Biol Chem 1982;257(6):2762

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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