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Argininosuccinate Synthase

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Definition: An enzyme of the urea cycle that catalyzes the formation of argininosuccinic acid from citrulline and aspartic acid in the presence of ATP. Absence or deficiency of this enzyme causes the metabolic disease CITRULLINEMIA in humans. EC 6.3.4.5.  /defic: consider also CITRULLINEMIA   
See Also Citrullinemia 		Other names Synthetase, Argininosuccinate; Synthase, Argininosuccinate; Argininosuccinate Synthetase
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
ArgG protein, E coli  EC 6.3.4.5   *Argininosuccinate Synthase *Escherichia coli Proteins. J Bacteriol 2003 May;185(10):3139-46
arginine synthetase system  0   *Argininosuccinate Lyase *Argininosuccinate Synthase *Multienzyme Complexes. Clin Nephrol 6(3):240;1975; Folia Psychiatr Neurol Jpn 29(1):77;1975; J Biol Chem 234:1769;1959; Kidney Int (Suppl) 7(3):S280;1975; Tohoku J Exp Med 127(4):379;1979

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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