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Autophagy

More information in Books or onNLM PubMed
Definition: The segregation and degradation of damaged or unwanted cytoplasmic constituents by autophagic vacuoles (cytolysosomes) composed of LYSOSOMES containing cellular components in the process of digestion; it plays an important role in BIOLOGICAL METAMORPHOSIS of amphibians, in the removal of bone by osteoclasts, and in the degradation of normal cell components in nutritional deficiency states.  programmed cell death unspecified probably    Other names Autophagocytosis; Deaths, Autophagic Cell; Death, Autophagic Cell; Cellular Autophagy; Cellular Autophagies; Cell Deaths, Autophagic; Cell Death, Autophagic; Autophagies, Cellular; Autophagies; Autophagic Cell Deaths; Programmed Cell Death, Type II; Autophagy, Cellular; Autophagic Programmed Cell Death; Autophagic Cell Death
 
SubstanceCAS Registry & nameCategoriesSource
NBR1 protein, Arabidopsis  0   *Carrier Proteins *Arabidopsis Proteins Autophagy. Autophagy. 2011 Sep;7(9):993-1010.
TORC1 protein complex, S cerevisiae  0   *Transcription Factors *Saccharomyces cerevisiae Proteins Autophagy. Autophagy. 2011 Aug 1;7(8):854-62
Atg8a protein, Drosophila  0   *Drosophila Proteins Autophagy. Autophagy 2008 Mar-Apr;4(2):
ATG5 protein, human  0   *Microtubule-Associated Proteins Autophagy. J Biol Chem. 2005 May 27;280(21):20722-9
Atg5 protein, mouse  0   *Microtubule-Associated Proteins Autophagy. Nature. 2004 Dec 23;432(7020):963
ATG12 protein, S cerevisiae  0   *Saccharomyces cerevisiae Proteins Autophagy.
Becn1 protein, mouse  0   *Apoptosis Regulatory Proteins Autophagy Genes, Tumor Suppressor. J Virol 1998 Nov;72(11):8586-96
ATG7 protein, S cerevisiae  0   *Saccharomyces cerevisiae Proteins Autophagy. Nature 1998 Sep 24;395(6700):395-8

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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