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Benserazide

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Definition: An inhibitor of DOPA DECARBOXYLASE that does not enter the central nervous system. It is often given with LEVODOPA in the treatment of parkinsonism to prevent the conversion of levodopa to dopamine in the periphery, thereby increasing the amount that reaches the central nervous system and reducing the required dose. It has no antiparkinson actions when given alone.     
Pharmacological Action Antiparkinson Agents; Dopamine Agents; Enzyme Inhibitors 		Other names Seryltrihydroxybenzylhydrazine; Serazide; Ro 44602; Ro 4 4602; Benzylhydrazine, Seryltrihydroxy; Seryltrihydroxy Benzylhydrazine; Ro 4-4602; DL-Serine 2-((2,3,4-trihydroxyphenyl)methyl)hydraz
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
benserazide, levodopa drug combination  0   *Benserazide *Levodopa Drug Combinations.
Pharma Action Enzyme Inhibitors ; Dopamine Agents 		Acta Neurol 28(2):208;1973; Acta Neurol Scand 53(3):189;1976; Br Med J 1(5957):573;1975; Wien Med Wochenschr 123(26):433;1973

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
Warning: the drugs or drug combinations referred to here may be similar or related, but are not be the same ones and may not have the same pharmacological action as other substances described on the same page or in the same row. Please refer to product monograph or to your doctor
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