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Carbonyl Cyanide m-Chlorophenyl Hydrazone

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Definition: A proton ionophore. It is commonly used as an uncoupling agent and inhibitor of photosynthesis because of its effects on mitochondrial and chloroplast membranes.     
Pharmacological Action Proton Ionophores 		Other names Carbonyl Cyanide meta-Chlorophenyl Hydrazone; CCCP; Carbonyl Cyanide meta Chlorophenyl Hydrazone; Carbonyl Cyanide m Chlorophenyl Hydrazone
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
carbonylcyanide 4-trifluoromethoxyphenylhydrazone  0   Carbonyl Cyanide m-Chlorophenyl Hydrazone/*analogs & derivatives. Biopharm Drug Dispos 1997 Oct;18(7):611-22
carbonylcyanide 4-chlorophenylhydrazone  946-76-9   Carbonyl Cyanide m-Chlorophenyl Hydrazone/*analogs & derivatives Ionophores. Mol Microbiol 1997 Mar;23(6):1107-20
4-chlorophenyl-N-methylhydrazonopropanedinitrile  51337-38-3   Carbonyl Cyanide m-Chlorophenyl Hydrazone/*analogs & derivatives. Gen Physiol Biophys 1993 Dec;12(6):533-42
carbonyl cyanide-4-nitro-2-chlorophenylhydrazone  3780-92-5   Carbonyl Cyanide m-Chlorophenyl Hydrazone/*analogs & derivatives. Gen Physiol Biophys 1993 Jun;12(3):213-29
carbonyl cyanide 2-nitrophenylhydrazone  55653-13-9   Carbonyl Cyanide m-Chlorophenyl Hydrazone/*analogs & derivatives. J Chromatogr 1988;455:344
4-azido-2-nitrocarbonylocyanide phenyl hydrazone  0   Carbonyl Cyanide m-Chlorophenyl Hydrazone/*analogs & derivatives. Arch Biochem Biophys 1984;232(2):610
carbonyl cyanide phenylhydrazone  306-18-3 Propanedinitrile, (phenylhydrazono)  Carbonyl Cyanide m-Chlorophenyl Hydrazone/*analogs & derivatives Uncoupling Agents. Biochem J 156(3):481;1976; Biochem J 156(3):493;1976
carbonylcyanide-4-trichloromethoxyphenylhydrazone  21609-11-0   Carbonyl Cyanide m-Chlorophenyl Hydrazone/*analogs & derivatives. Biochem Biophys Res Comm 64(2):790;1975

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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