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Cephalexin
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Definition
: A semisynthetic cephalosporin antibiotic with antimicrobial activity similar to that of CEPHALORIDINE or CEPHALOTHIN, but somewhat less potent. It is effective against both gram-positive and gram-negative organisms.
Pharmacological Action
Anti-Bacterial Agents
Examples
Cefaclor
;
Cefadroxil
;
Cephaloglycin
;
Cephradine
Other names
Monosodium Salt Cephalexin; Monohydrochloride, Monohydrate Cephalexin; Monohydrochloride, Cephalexin; Monohydrate, Cephalexin; Monohydrate Cephalexin Monohydrochloride; Hydrochloride, Cephalexin; Hemihydrate, Cephalexin; Dihydride, Cephalexin; Palitrex; Ceporexine; Cephalexin, Monosodium Salt, (6R-
(6alpha,7beta))-
I; Cephalexin, Monosodium Salt; Cephalexin, (6R-
(6alpha,7beta))-
Isomer; Cephalexin, (6R-
(6alpha,7beta(S*)))-
Isomer; Cephalexin, (6R-
(6alpha,7alpha(R*)))-
Isomer; Cephalexin Monohydrochloride, Monohydrate; Cephalexin Monohydrochloride; Cephalexin Monohydrate; Cephalexin Hydrochloride; Cephalexin Hemihydrate
Drugs
*
:
PANIXINE DISPERDOSE
;
KEFLEX
;
CEPHALEXIN
;
KEFLET
;
KEFTAB
Substance
CAS Registry & name
Categories
Source
Drugs
*
kufaprim
90509-95-8 5-
Thia-
1-
azabicyclo(4.2.0)oct-
2-
ene-
2-
carboxylic acid, 7-
((aminophenylacetyl)amino)-
3-
methyl-
8-
oxo-
, (6R-
(6alpha,7beta(R*)))-
, mixt. with (2R-
cis)-
(3-
methyloxiranyl)phosphonic acid
Cephalexin
Fosfomycin.
Chir Patol Sper 1983;31(4):149
Flucexin
79806-18-1 5-
Thia-
1-
azabicyclo(4.2.0)oct-
2-
ene-
2-
carboxylic acid, 7-
((aminophenylacetyl)amino)-
3-
methyl-
8-
oxo-
, (6R-
(6alpha,7beta(R*)))-
, mixt. with (2S-
(2alpha,5alpha,6beta))-
6-
(((3-
(2-
chloro-
6-
fluorophenyl)-
5-
methyl-
4-
isoxazolyl)carbonyl)amino)-
3,3-
dimethyl-
7-
oxo
Cephalexin
Floxacillin.
G Ital Chemioter 1980;27(1):23
cefems
0
Cephalexin/*analogs & derivatives.
G Ital Chemioter 1979;26(2):257
lysine cephalexin
57683-74-6
Cephalexin/*analogs & derivatives.
Arzneim Forsch 29(10):1547;1979
pivcephalexin
63836-75-9 (6R-
(6 alpha,7 beta(R*)))-
7-
((aminophenylacetyl)amino)-
3-
methyl-
8-
oxo-
5-
thia-
1-
azabicyclo(4.2.0)oct-
2-
ene-
2-
carboxylic acid, (2,2-
dimethyl-
1-
oxopropoxy)methyl ester
Cephalexin/*analogs & derivatives.
Arzneim Forsch 27(4):819;1977; Bronchopneumologie 29(4):346;1979
4',5'-
dihydrocefradine
37051-00-6 5-
Thia-
1-
azabicyclo(4.2.0)oct-
2-
ene-
2-
carboxylic acid, 7-
((amino-
1-
cyclohexen-
1-
ylacetyl)amino)-
3-
methyl-
8-
oxo-
, (6R-
(6alpha,7beta(R*)))
Cephalexin/*analogs & derivatives.
Antibiotics 29(5):559;1976