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Cephamycins

More information in Books or onNLM PubMed
Definition: Naturally occurring family of beta-lactam cephalosporin-type antibiotics having a 7-methoxy group and possessing marked resistance to the action of beta-lactamases from gram-positive and gram-negative organisms.     
Pharmacological Action Anti-Bacterial Agents
Examples Cefmetazole; Cefotetan; Cefoxitin 		Other names Antibiotics, Cephamycin; Cephamycin Antibiotics
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
cefminox  84305-41-9 5-Thia-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylic acid, 7-((((2-amino-2-carboxyethyl)thio)acetyl)amino)-7-methoxy-3-(((1-methyl-1H-tetrazol-5-yl)thio)methyl)-8-oxo-, (6R-(6alpha,7alpha,7(S*)))  *Cephamycins.
Pharma Action Anti-Bacterial Agents 		Microbiol Immunol 1983;27(8):649
SF 1623B  58301-37-4 5-Thia-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylic acid, 7-((5-amino-5-carboxy-1-oxopentyl)amino)-3-(hydroxymethyl)-7-methoxy-8-oxo-, (6R-(6alpha,7alpha,7(R*)))  *Cephamycins. J Antibiot (Tokyo) 1983;23(2):115
SF 1623  56487-86-6 5-Thia-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylic acid, 7-((5-amino-5-carboxy-1-oxopentyl)amino)-7-methoxy-8-oxo-3-((sulfothio)methyl)-, (6R-(6alpha,7alpha,7(R*)))  *Cephamycins. J Antibiot (Tokyo) 1983;36(2):115
cefbuperazone  76610-84-9 5-Thia-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylic acid, 7-((2-(((4-ethyl-2,3-dioxo-1-piperazinyl)carbonyl)amino)-3-hydroxy-1-oxobutyl)amino)-7-methoxy-3-(((1-methyl-1H-tetrazol-5-yl)thio)methyl)-8-oxo-, (6R-(6alpha,7alpha,7(2R*,3S*)))  *Cephamycins. Jpn J Antibiot 1982;35(9):2139
oganomycins  76822-80-5 Oganomycin  *Cephamycins. J Antibiot (Tokyo) 1980;33(9):1074; J Antibiot (Tokyo) 1981;34(11):1507
cephamycin C  38429-35-5   *Cephamycins. Antimicrob Agents Chemother 1(3):237;1972; Biochem J 1980;186(2):613
SQ 14359  65700-47-2 5-Thia-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylic acid, 7-((((aminocarbonyl)amino)-2-thienylacetyl)amino)-7-methoxy-3-(((1-methyl-1H-tetrazol-5-yl)thio)methyl)-8-oxo-, (6R-(6alpha,7alpha,7(S*)))  *Cephamycins. J Antibiot (Tokyo) 31(10):1046;1978
C 2801X  56083-50-2 5-thia-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylic acid, 7-((5-amino-5-carboxy-1-oxopentyl)amino)-3-(((3-(3,4-dihydroxyphenyl)-2-methoxy-1-oxo-2-propenyl)oxy)methyl)-7-methoxy-8-oxo-, (6R-(6 alpha,7 alpha,7(R*)))  *Cephamycins. J Antibiot (Tokyo) 29(2):113;1976

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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