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Cerebroside-Sulfatase

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Definition: An enzyme that catalyzes the hydrolysis of cerebroside 3-sulfate (sulfatide) to yield a cerebroside and inorganic sulfate. A marked deficiency of arylsulfatase A, which is considered the heat-labile component of cerebroside sulfatase, has been demonstrated in all forms of metachromatic leukodystrophy (LEUKODYSTROPHY, METACHROMATIC). EC 3.1.6.8.  /defic: consider also LEUKODYSTROPHY, METACHROMATIC   
See Also Leukodystrophy, Metachromatic 		Other names Sulfatidate Sulfatase; Arylsulfatase A; Sulfatase, Sulfatidate; Cerebroside Sulfatase
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
galactocerebroside sulfate sulfatidase  EC 3.1.6.-   *Cerebroside-Sulfatase. J Biol Chem 1995 Apr 28;270(17):10187-92

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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