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Chromogranins

More information in Books or onNLM PubMed
Definition: A group of acidic proteins that are major components of SECRETORY GRANULES in the endocrine and neuroendocrine cells. They play important roles in the aggregation, packaging, sorting, and processing of secretory protein prior to secretion. They are cleaved to release biologically active peptides. There are various types of granins, usually classified by their sources.     
Examples Chromogranin A; Chromogranin B; Secretogranin II 		Other names Secretogranins; Granins
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
secretogranin IV  0   *Chromogranins.
secretogranin III  0   *Chromogranins.
secretogranin 3, rat  0   *Chromogranins.
secretogranin 3, mouse  0   *Chromogranins.
SCG3 protein, human  0   *Chromogranins.
chromogranin A-derived peptide, WE-14  115136-18-0   *Neoplasm Proteins *Chromogranin A Carcinoid Tumor Chromogranins. FEBS Lett 1992 Apr 27;301(3):319-21
beta-granins  0   *Chromogranins. FEBS Lett 1985;188(2):336
chromomembrin B  0   *Chromogranins. J Neurochem 20(4):977;1973; J Neurochem 27(6):1539;1976
chromomembrin A  0   *Chromogranins. Biochem J 129(1):187;1972

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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