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Clomiphene

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Definition: A triphenyl ethylene stilbene derivative which is an estrogen agonist or antagonist depending on the target tissue.     
Pharmacological Action Estrogen Antagonists; Fertility Agents, Female; Selective Estrogen Receptor Modulators 		Other names Zuclomiphene; Enclomiphene; Clomifene; Chloramiphene; trans Clomiphene Citrate; Hydrochloride, Clomiphene; En Clomiphene; Citrate, trans-Clomiphene; Citrate, Enclomiphene; Citrate, Clomiphene; trans-Clomiphene Citrate; Zuclomifene; Serophene; Klostilbegit; Gravosan; Enclomiphene Citrate; Enclomiphen; Enclomifene; En-Clomiphene; DynericDrugs* : MILOPHENE; CLOMIPHENE CITRATE; CLOMID; SEROPHENE
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
MDL 101986  0   Clomiphene/*analogs & derivatives. Biochem Pharmacol 1998 Mar 15;55(6):841-51
MDL 103323  0   Clomiphene/*analogs & derivatives. Biochem Pharmacol 1998 Mar 15;55(6):841-51
1-(4-(2-(diethylamino)ethoxy)-phenyl)-1-(phenyl)-2-(3-methoxy-4-hydroxyphenyl)-2-chloroethane  117095-65-5   Clomiphene/*analogs & derivatives. J Med chem 1989;32(1):192
1-(phenyl)-1-(4-(2-(diethylamino)-ethoxy)phenyl)-2-(4-hydroxyphenyl)-2-chloroethane  117095-64-4   Clomiphene/*analogs & derivatives. J Med Chem 1989;32(1):192
3-methoxy-4-hydroxyclomiphene  117095-59-7   Clomiphene/*analogs & derivatives. J Med Chem 1989;32(1):192
1-(4-fluorophenyl)-1-(4-(2-N,N-diethylamino)ethoxy)phenyl-2-phenylethylene  110465-94-6   Clomiphene/*analogs & derivatives. Steroids 1987;48(1-2):73
4-hydroxyclomiphene  79838-51-0   Clomiphene/*analogs & derivatives. Biochem Biophys Res Commun 1986;140(2):523
2-(4-(2-bromo-1,2-diphenylvinyl)phenoxy)triethylamine  62040-71-5 Ethanamine, 2-(4-(2-bromo-1,2-diphenylethenyl)phenoxy)-N,N-diethyl-, (E)  Clomiphene/*analogs & derivatives. J Pharm Sci 65(10):1545;1976
EIPW 103  19957-52-9 2-(4-(1,2-diphenylethenyl)phenoxy)-N,N-diethylethanamine  *Stilbenes Clomiphene. Br J Pharmacol 46(2):324;1972
EIPW 113  37820-57-8   Clomiphene/*analogs & derivatives. Br J Pharmacol 46(2):324;1972
1-(p-(beta-diethylaminoethoxy)phenyl)-2-nitro-1,2-diphenylethylene  13542-78-4 N,N-diethyl-2-(4-(2-nitro-1,2-diphenylethenyl)phenoxy)ethanamine  Clomiphene/*analogs & derivatives. Fertil Steril 23(5):339;1972

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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