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Cobamides

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Definition:   deficiency: coordinate COBAMIDES /defic (IM) with VITAMIN B 12 DEFICIENCY (IM)   
Pharmacological Action Vitamin B Complex 		Other names Vitamin B 12 Coenzymes; Deoxyadenosinecobalamins; Coenzymes, Vitamin B12; B12 Coenzymes, Vitamin; Vitamin B12 Coenzymes
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
beta-cyano-neocobyrate  0   *Cobamides. Chemistry 2008;14(25):7521-4
adenosyl cobyrinic acid a,c-diamide  0   *Cobamides. Biochemistry 2007 Dec 11;46(49):13983-93
adenosylcobinamide phosphate  0   *Cobamides *Phosphoric Acid Esters. J Bacteriol 2007 Oct;189(20):7310-5
5'-deoxy-3',4'-anhydroadenosylcobalamin  0   *Cobamides. Biochemistry 2006 Dec 5;45(48):14362-70
3-isoadenosylcobalamin  0   *Cobamides. J Inorg Biochem. 2004 Feb;98(2):287-300
8-methoxy-5'-deoxyadenosylcobalamin  0   *Cobamides. J Inorg Biochem 2002 Aug 15;91(2):388-99
adenosylcobinamide 2-chlorophenyl phosphate  0   *Cobamides. J Inorg Biochem 2002 Aug 15;91(2):371-87
adensoylcobinamide  0   *Cobamides. J Biol Chem 2000 Sep 8;275(36):27576-86
guanosine 5'-(5'-deoxyadenosylcobinamide pyrophosphate)  0   *Cobamides Guanosine Diphosphate/*analogs & derivatives. J Bacteriol 2000 Aug;182(15):4227-33
DMA-methyltransferase  EC 2.1.1.-   *Cobamides *Methyltransferases. Eur J Biochem 1998 May 1;253(3):692-7
4-aza-5,6-dimethylbenzimidazolylcobamide  0   *Cobamides. Z Naturforsch (C) 1997 May-Jun;52(5-6):287-91
7-azabenzimidazolylcobamide  0   *Cobamides. Biol Chem Hoppe Seyler 1995 Oct;376(10):595-601
5,6-dimethyl-7-azabenzimidazolylcobamide  0   *Cobamides. Biol Chem Hoppe Seyler 1995 Oct;376(10):595-601
adenosylcobinamide methyl phosphate  147736-07-0   *Cobamides. Biochemistry 1993 Feb 16;32(6):1535-40
Coalpha-(alpha-5,6-dimethylbenzimidazolyl)-Cobeta-cyanocobamide  143481-69-0   *Cobamides. J Biol Chem 1992 Jul 5;267(19):13302-5
CobV protein, Pseudomonas denitrificans  EC 2.6.99.-   *Bacterial Proteins *Nitrogenous Group Transferases Cobamides. J Bacteriol 1991;173(19):6066
phenolyl cobamide  125939-05-1   *Cobamides. Eur J Biochem 1989;186(3):657
Coalpha-(alpha-(5-methoxy-6-methylbenzimidazolyl))-Cobeta-cyanocobamide  0   *Cobamides. Eur J Biochem 1988;172(2):459
4-cresolylcobamide  119637-75-1   *Cobamides. Eur J Biochem 1988;172(2):459
2-methylsulfonyladenylcobamide  107672-06-0   *Cobamides. Eur J Biochem 1987;163(1):175
2-methylsulfinyladenylcobamide  107688-04-0   *Cobamides. Eur J Biochem 1987;163(1):175
(2-hydroxy-5,6-dimethylbenzimidazolyl)cobamide  90654-05-0 Cobinamide, cyanide hydroxide, dihydrogen phosphate (ester), inner salt, 3'-ester with 1,3-dihydro-1-alpha-D-ribofuranosyl-2H-benzimidazol-2-one-2-14C  *Cobamides. Hoppe Seylers Z Physiol Chem 1984;365(2):137
(2-amino-5,6-dimethylbenzimidazolyl)cobamide  90654-06-1 Cobinamide, cyanide hydroxide, dihydrogen phosphate (ester), inner salt, 3'-ester with 1-alpha-D-ribofuranosyl-1H-benzimidazol-2-amine-2-14C  *Cobamides. Hoppe Seylers Z Physiol Chem 1984;365(2):137
cobamamide 5'-phosphate  39044-48-9 Cobinamide, Co-(5'-deoxyadenosine-5') deriv., hydroxide, dihydrogen phosphate (ester), inner salt, 3'-ester with 5,6-dimethyl-1-(5-O-phosphono-alpha-D-ribofuranosyl)-1H-benzimidazole  *Cobamides. Biochim Biophys Acta 1981;678(3):300
cobinamide  13497-85-3   *Cobamides. J Clin Invest 61(6):1628;1978
thiobanzyme  79028-53-8 Cobinamide, Co-(5'-deoxyadenosine-5') deriv., hydroxide, dihydrogen phosphate (ester), inner salt, 3'-ester with 5,6-dimethyl-1-alpha-D-ribofuranosyl-1H-benzimidazole, mixt. with 3-((4-amino-2-methyl-5-pyrimidinyl)methyl)-5-(2-hydroxyethyl)-4-methylthiaz  *Cobamides *Pyridoxine *Thiamine Drug Combinations. J Sci Med Lille 89(11):441;1971
cobamamide  13870-90-1 desoxy-5'-adenosine-5' alpha-(dimethyl-5,6-benzimidazolyl)cobamide  *Cobamides. Am J Clin Nutr 1980;33(1):77; Arch Biochem Biophys 189(2):441;1978; Arch Biochem Biophys 1980;200(1):130; Biochem J 172:115;1978; Biochemistry 17(11):2218;1978; Biochemistry 1979;18(13):2776; Biokhimiia 44(3):467;1979; Farmaco 27(12):699;1972; Inform Dentaire 48:49;1975; J Am Chem Soc 98(20):6331;1976; J Biol Chem 253(4):1041;1978; Methods Enzymol 1980;67:57; Sem Hop Ther 51(5-6):315;1975; Sem Hop Ther 52(10):533;1976

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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