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Coenzyme A Ligases

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Definition: Enzymes that catalyze the formation of acyl-CoA derivatives. EC 6.2.1.     
Examples Acetate-CoA Ligase; Succinate-CoA Ligases 		Other names Coenzyme A Synthetases; Acyl Coenzyme A Synthetases; Acyl CoA Synthetases; Synthetases, Coenzyme A; Synthetases, Acyl CoA; Ligases, Coenzyme A; Ligases, Co A; Ligases, Acid-Thiol; CoA Synthetases, Acyl; Acid Thiol Ligases; A Synthetases, Coenzyme; A Ligases, Coenzyme; A Ligases, Co; Co A Ligases; Acid-Thiol Ligases
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
acyl-CoA synthetase 4, mouse  EC 6.2.1.-   *Coenzyme A Ligases. Biochem Biophys Res Commun. 2012 Mar 16;419(3):505-10.
Acsl1 protein, rat  EC 6.2.1.3   *Coenzyme A Ligases. FEBS J. 2011 May;278(9):1522-32
ACSF3 protein, human  EC 6.2.1.-   *Coenzyme A Ligases. Nat Genet 2011 Sep;43(9):883-6
ACN1 protein, Arabidopsis  EC 6.2.1.-   *Coenzyme A Ligases *Arabidopsis Proteins. Biochem J 2011 Aug 1;437(3):505-13
Slc27a2 protein, rat  EC 6.2.1.-   *Coenzyme A Ligases. Int J Obes (Lond) 2010 May;34(5):831-9
acetoacetyl-CoA synthase, Streptomyces  EC 6.2.1.-   *Bacterial Proteins *Coenzyme A Ligases. Proc Natl Acad Sci U S A 2010 Jun 22;107(25):11265-70
LACS1 protein, Arabidopsis  EC 6.2.1.-   *Coenzyme A Ligases *Arabidopsis Proteins. Planta. 2010 Apr;231(5):1089-100
ACSL1 protein, mouse  EC 6.2.1.-   *Coenzyme A Ligases. J Biol Chem 2009 Jul 3;284(27):18347-56
ACOS5 protein, Arabidopsis  EC 3.6.1.-   *Coenzyme A Ligases *Arabidopsis Proteins. Plant Cell 2009 Feb;21(2):507-25
ACSM2A protein, human  EC 6.2.1.2   *Coenzyme A Ligases. J Mol Biol 2009 May 22;388(5):997-1008
AAE18 protein, Arabidopsis  EC 6.2.6.-   *Coenzyme A Ligases *Arabidopsis Proteins. Plant Mol Biol 2009 Mar;69(5):503-15
AAE14 protein, Arabidopsis  EC 6.2.1.-   *Coenzyme A Ligases *Arabidopsis Proteins. Plant J 2008 Apr;54(2):272-83
FATP2 protein, mouse  EC 6.2.1.-   *Coenzyme A Ligases. Biol Pharm Bull 2007 Nov;30(11):2185-90
BZO1 protein, Arabidopsis  EC 6.2.1.25   *Coenzyme A Ligases *Arabidopsis Proteins. Plant J 2007 Sep;51(6):1062-76
LACS2 protein, Arabidopsis  EC 6.2.1.-   *Coenzyme A Ligases *Arabidopsis Proteins. Plant Physiol 2007 Jun;144(2):1093-103
SanJ protein, Streptomyces ansochromogenes  EC 6.2.1.-   *Coenzyme A Ligases. Yi Chuan Xue Bao 2001;28(2):188-95
Faa1 protein, S cerevisiae  EC 6.2.1.-   *Coenzyme A Ligases. J Cell Biol 1992 May;117(3):515-29
4CL4 protein, Arabidopsis  EC 6.2.1.-   *Coenzyme A Ligases *Arabidopsis Proteins. BMC Biotechnol 2006;6:22
4CL1 protein, Arabidopsis  EC 6.2.1.-   *Coenzyme A Ligases *Arabidopsis Proteins. Plant Mol Biol 1995 Aug;28(5):871-84
Acsl5 protein, rat  EC 6.2.1.3   *Coenzyme A Ligases *Mitochondrial Proteins. J Biol Chem 2006 Jan 13;281(2):945-50
At5g63380 protein, Arabidopsis  EC 6.2.1.12   *Coenzyme A Ligases *Arabidopsis Proteins. J Biol Chem 2005 Apr 8;280(14):13962-72
At4g05160 protein, Arabidopsis  EC 6.2.1.12   *Coenzyme A Ligases *Arabidopsis Proteins. J Biol Chem 2005 Apr 8;280(14):13962-72
Acsl4 protein, rat  EC 6.2.1.-   *Coenzyme A Ligases. Endocr Res 2004 Nov;30(4):623-7
Acsl6 protein, rat  EC 6.2.1.-   *Coenzyme A Ligases. Biochemistry 2005 Feb 8;44(5):1635-42
cyclohexanecarboxylate-CoA ligase  EC 6.2.1.-   *Coenzyme A Ligases. Proc Natl Acad Sci U S A 1997 Jun 10;94(12):6484-9
Bucs1 protein, mouse  EC 6.2.1.-   *Coenzyme A Ligases.
citryl-CoA synthetase  EC 6.2.1.-   *Coenzyme A Ligases. Mol Microbiol. 2004 May;52(3):751-61
CG6178 protein, Drosophila  EC 6.2.1.3   *Coenzyme A Ligases *Drosophila Proteins. Gene 2004 Mar 31;329:137-45
ACSM3 protein, human  EC 6.2.1.-   *Coenzyme A Ligases. Hypertens Res 2003 Aug;26(8):591-5
Facl5 protein, rat  EC 6.2.1.3   *Coenzyme A Ligases.
ACSL5 protein, human  EC 6.2.1.3   *Coenzyme A Ligases.
Acsl6 protein, mouse  EC 6.2.1.3   *Coenzyme A Ligases. Biochem Biophys Res Commun 2003 Jun 13;305(4):925-33
LACS7 protein, Arabidopsis  EC 6.2.1.3   *Coenzyme A Ligases *Arabidopsis Proteins. Plant J 2002 Oct;32(1):93-103
LACS6 protein, Arabidopsis  EC 6.2.1.3   *Coenzyme A Ligases *Arabidopsis Proteins. Plant J 2002 Oct;32(1):93-103
LACS9 protein, Arabidopsis  EC 6.2.1.3   *Coenzyme A Ligases *Arabidopsis Proteins. Plant Physiol 2002 Aug;129(4):1700-9
ACS6 protein, Brassica napus  EC 6.2.1.-   *Coenzyme A Ligases *Plant Proteins. Plant Mol Biol 2001 Dec;47(6):717-26
DpgA protein, Amycolatopsis mediterranei  0   *Bacterial Proteins *Coenzyme A Ligases. J Biol Chem 2001 Oct 19;276(42):38370-7
Sa ligase  EC 6.2.1.-   *Coenzyme A Ligases. J Biol Chem 2001 Sep 21;276(38):35961-6
ACSM1 protein, human  EC 6.2.1.-   *Coenzyme A Ligases. J Biol Chem 2001 Sep 21;276(38):35961-6
Facl2 protein, rat  EC 6.2.1.-   *Coenzyme A Ligases. J Biol Chem 2001 Jul 6;276(27):24667-73
lipidosin  EC 6.2.1.-   *Coenzyme A Ligases. Biochem Biophys Res Commun 2000 Dec 9;279(1):62-8
3-hydroxybenzoate coenzyme A ligase  EC 6.2.1.-   *Coenzyme A Ligases. Biol Chem 2000 Feb;381(2):155-60
YbtE protein, Yersinia pestis  EC 6.2.1.-   *Bacterial Proteins *Coenzyme A Ligases. Infect Immun 1997 May;65(5):1659-68
ACSL6 protein, human  EC 6.2.1.3   *Coenzyme A Ligases. Genes Chromosomes Cancer 1999 Nov;26(3):192-202
feruloyl-coenzyme A synthetase  EC 6.2.1.-   *Coenzyme A Ligases. Appl Environ Microbiol 1999 Nov;65(11):4837-47
bgm protein, Drosophila  EC 6.2.1.3   *Coenzyme A Ligases *Drosophila Proteins Adrenoleukodystrophy. Science 1999 Jun 18;284(5422):1985-8
3-methylmuconolactone-CoA synthetase  EC 6.2.1.-   *Coenzyme A Ligases. J Bacteriol 1998 Dec;180(24):6668-73
acyl CoA synthetase 5  EC 6.2.1.-   *Coenzyme A Ligases. J Biochem (Tokyo) 1998 Sep;124(3):679-85
xenobiotic medium chain fatty acid - coenzyme A ligase  EC 6.2.1.-   *Coenzyme A Ligases Xenobiotics. Biochim Biophys Acta 1997 Jun 23;1346(3):231-6
acetate-CoA ligase (ADP-forming)  EC 6.2.1.13   *Coenzyme A Ligases. J Bacteriol 1996 Oct;178(20):5897-903
pseudoecgonyl-CoA synthetase  EC 6.2.1.-   *Coenzyme A Ligases. Appl Environ Microbiol 1996 Jan;62(1):94-9
caiC protein, E coli  EC 6.2.1.-   *Coenzyme A Ligases *Escherichia coli Proteins. Mol Microbiol 1994 Sep;13(5):775-86
FAA2 protein, S cerevisiae  EC 6.2.1.3   *Coenzyme A Ligases *Saccharomyces cerevisiae Proteins. EMBO J 1994 Dec 1;13(23):5531-8
acyl-coenzyme A synthetase, E coli  EC 6.2.1.-   *Coenzyme A Ligases *Escherichia coli Proteins Carrier Proteins. Mol Gen Gent 1994 Feb;242(3):241-9
DCQVA-CoA synthetase  EC 6.2.1.-   *Coenzyme A Ligases. Biochem J 1993 Nov 15;296(Pt 1):265-70
phytanoyl-CoA ligase  EC 6.2.1.-   *Coenzyme A Ligases. FEBS Lett 1993 May 10;322(2):101-4
myristoyl-CoA synthetase  EC 6.2.1.-   *Coenzyme A Ligases. J Biol Chem 1993 Mar 5;268(7):4889-902
pimeloyl-CoA synthetase  EC 6.2.1.-   *Coenzyme A Ligases. Biochem J 1992 Nov 1;287( Pt 3):685-90
4-halobenzoate-CoA ligase  EC 6.2.1.-   *Coenzyme A Ligases. Biol Chem Hoppe Seyler 1992 Oct;373(10):1001-7
2-aminobenzoate coenzyme A ligase  EC 6.2.1.-   *Coenzyme A Ligases. J Bacteriol 1991;173(17):5494
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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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