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Cortisone Reductase

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Definition: An enzyme that catalyzes the interconversion of a ketone and hydroxy group at C-20 of cortisone and other 17,20,21-trihydroxy steroids. EC 1.1.1.53.      Other names 20-beta-Hydroxysteroid Dehydrogenase; Reductase, Cortisone; Dehydrogenase, 20-beta-Hydroxysteroid; 20 beta Hydroxysteroid Dehydrogenase; 3 alpha,20 beta Hydroxysteroid Dehydrogenase
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
17-(1-oxo-3-ethoxy-2-propynyl)androst-4-en-3-one  104849-33-4   *Androstenes Cortisone Reductase/antagonists & inhibitors. Biochemistry 1986;25(23):7288

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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