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Ancitabine

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Definition: Congener of CYTARABINE that is metabolized to cytarabine and thereby maintains a more constant antineoplastic action.     
Pharmacological Action Antimetabolites, Antineoplastic
Other names Cyclocytidine; Anhydro-Ara-C; U33624A; U33,624A; U 33624A; U 33,624A; NSC145668; NSC145,668; NSC 145668; NSC 145,668; CycloC; Cyclo C; U-33624A; U-33,624A; NSC-145668; NSC-145,668; Cyclo-C
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
1-(2,3-anhydrolyxofuranosyl)cytosine  34989-27-0   Ancitabine/*analogs & derivatives. J Med Chem 1988;31(7):1475
5-fluoro-2,2'-cyclocytidine  40505-45-1 2,2'-anhydro-1-beta-D-arabinofuranosyl-5-fluorocytosine  Ancitabine/*analogs & derivatives. Ann N.Y. Acad Sci 255:59-213;1975; Cancer Chemother Rep 59(5):1019;1975; Cancer Clin Trials 1978;1(4):289; Cancer Res 37(11):4098;1977; Cancer Treat Rep 61(4):617;1977; Cancer Treatment Repts 62(3):463;1978; Eur J Cancer 14(2):195;1978; Gann 66(5):561;1975; Gastrointest Res 5:71;1979; J Med Chem 20(3):344;1977
2,2'-anhydro-4'-thio-1-beta-D-arabinofuranosylcytosine  52749-52-7 6H-Thieno(2',3':4,5)oxazolo(3,2-a)pyrimidine-2-methanol, 2,3,3a,9a-tetrahydro-3-hydroxy-6-imino-, monohydrochloride, (2R-(2alpha,3beta,3abeta,9abeta))  Ancitabine/*analogs & derivatives. J Med Chem 17(5):537;1974

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012

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