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Hemoglobin A, Glycosylated

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Definition: Minor hemoglobin components of human erythrocytes designated A1a, A1b, and A1c. Hemoglobin A1c is most important since its sugar moiety is glucose covalently bound to the terminal amino acid of the beta chain. Since normal glycohemoglobin concentrations exclude marked blood glucose fluctuations over the preceding three to four weeks, the concentration of glycosylated hemoglobin A is a more reliable index of the blood sugar average over a long period of time.  urine: coord IM with HEMOGLOBINURIA (IM); DF: note short X refs    Other names Hemoglobin A(1); HbA1; Hb A1c; Glycosylated Hemoglobin A; Glycohemoglobin A; Hemoglobins, Glycated; Hemoglobin, Glycosylated A1a 1; Glycosylated Hemoglobin; Glycosylated A1b Hemoglobin; Glycosylated A1a-1 Hemoglobin; A1b Hemoglobin, Glycosylated; A1a-1 Hemoglobin, Glycosylated; Hemoglobin, Glycosylated A1b; Hemoglobin, Glycosylated A1a-1; Hemoglobin, Glycosylated; Hb A1b; Hb A1a-2; Hb A1a-1; Hb A1a+b; Hb A1
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
HbA(1c) protein, mouse  0   *Hemoglobin A, Glycosylated. Pharmacol Res. 2011 Apr;63(4):284-93
hemoglobin A1c protein, human  0   *Hemoglobin A, Glycosylated. Clin Chim Acta 2007 Feb;377(1-2):114-8
hemoglobin A1d  0   *Hemoglobin A, Glycosylated. Clin Chem 1995 May;41(5):658-63
hemoglobin A, glycosylated-nitric oxide complex  0   *Hemoglobin A, Glycosylated *Nitric Oxide. J Inorg Biochem 1988;34(1):19
pre-hemoglobin A, glycosylated  0   *Hemoglobin A, Glycosylated *Protein Precursors. Acta Pediatr Scand 1983;72(6):911
glucosylated hemoglobin A  0   Hemoglobin A, Glycosylated/*analogs & derivatives. Diabetes 1980;29(7):524

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012

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