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Hexamethonium Compounds
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Definition
: Compounds containing the hexamethylenebis(trimethylammonium) cation. Members of this group frequently act as antihypertensive agents and selective ganglionic blocking agents.
antihypertensives; DF: HEXAMETHONIUM CPDS
Pharmacological Action
Antihypertensive Agents
;
Ganglionic Blockers
Examples
Hexamethonium
Other names
Compounds, Hexamethonium
Substance
CAS Registry & name
Categories
Source
Drugs
*
N,N'-
(2,3-
dihydroxybenzyl)-
N,N,N',N'-
tetramethyl-
1,6-
hexanediamine
159662-70-1
*Catechols
*Hexamethonium Compounds.
J Med Chem 1994 Dec 9;37(25):4417-20
CHIN 3-
6
155114-46-8 1,6-
Hexanediaminium, N,N'-
bis(3-
(3,4-
dihydro-
4-
oxo-
2-
phenyl-
1(2H)-
quinazolinyl)propyl)-
N,N,N',N'-
tetramethyl-
, dibromide
*Hexamethonium Compounds
*Quinazolines.
J Pharm Pharmacol 1994 Feb;46(2):108-12
hylan gel
0
*Cellulose
*Hexamethonium Compounds
*Tantalum
*Thrombin
Drug Combinations
Hyaluronic Acid/*analogs & derivatives
Biocompatible Materials
Embolization, Therapeutic.
J Biomed Mater Res 1991;25(6):699
benzohexonium
971-60-8 N,N,N,N',N',N'-
hexamethyl-
1,6-
hexanediaminium, dibenzenesulfonate
*Hexamethonium Compounds.
Pharma Action
Anti-Ulcer Agents
;
Ganglionic Blockers
Klin Khir 8:53;1979; Terapev Arkhiv 49(1):45;1977
hexafluorenium
4844-10-4
*Fluorenes
*Hexamethonium Compounds.
Anaesthesia 33(7):649;1978; Arch Int Pharmacodyn Ther 225(2):196;1977; Br J Anaesth 47(8):885;1975; Jpn J Anesthesiol 26(5):534;1977; Naunyn Schmiedebergs Arch Pharmacol 293(1):11;1976; Rev Esp Anestesiol Reanim 25(5):426;1978
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